Evidence map›Paper›PMID 36132856›Full record

ArticleNanoscale advances2021

Investigating the reactive oxygen species production of Rose Bengal and Merocyanine 540-loaded radioluminescent nanoparticles.

Anne Nsubuga, Gabrielle A Mandl, John A Capobianco

Abstract read
In one paragraph

Article in Nanoscale advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anne NsubugaDepartment of Chemistry and Biochemistry, Centre for NanoScience Research, Concordia University 7141 Rue Sherbrooke Ouest Montreal QC H4B 1R6 Canada John.capobianco@concordia.ca.
Gabrielle A MandlDepartment of Chemistry and Biochemistry, Centre for NanoScience Research, Concordia University 7141 Rue Sherbrooke Ouest Montreal QC H4B 1R6 Canada John.capobianco@concordia.ca.ORCID https://orcid.org/0000-0001-6630-4371
John A CapobiancoDepartment of Chemistry and Biochemistry, Centre for NanoScience Research, Concordia University 7141 Rue Sherbrooke Ouest Montreal QC H4B 1R6 Canada John.capobianco@concordia.ca.ORCID https://orcid.org/0000-0002-2892-5211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioluminescent nanomaterials have garnered significant attention in the past decade due to their potential to perform X-ray mediated photodynamic therapy (X-PDT). Many of these materials are assumed to produce singlet oxygen based on a single assay. Herein we demonstrate that multiple assays are required to confidently determine whether singlet oxygen or other reactive oxygen species are being produced through type I or type II PDT mechanisms. Rose Bengal and Merocyanine 540 photosensitizers were loaded into mesoporous silica-coated NaLuF

Identifiers

PMID36132856
PMCPMC9417208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.