Evidence map›Paper›PMID 36132786›Full record

ArticleNanoscale advances2020

Highly swelling pH-responsive microgels for dual mode near infra-red fluorescence reporting and imaging.

Mingning Zhu, Dongdong Lu, Qing Lian, Shanglin Wu, Wenkai Wang, L Andrew Lyon, Weiguang Wang, Paulo Bártolo, Mark Dickinson, Brian R Saunders

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Chemically Fueled Volume Phase Transition of Polyacid Microgels.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Mingning ZhuDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.ORCID https://orcid.org/0000-0002-2246-6552
Dongdong LuDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.
Qing LianDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.
Shanglin WuDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.ORCID https://orcid.org/0000-0001-9910-8115
Wenkai WangDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.
L Andrew LyonSchmid College of Science and Technology, Chapman University Orange CA 92866 USA.
Weiguang WangDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering, University of Manchester Manchester M13 9PL UK.ORCID https://orcid.org/0000-0002-8959-329X
Paulo BártoloDepartment of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering, University of Manchester Manchester M13 9PL UK.ORCID https://orcid.org/0000-0003-3683-726X
Mark DickinsonPhoton Science Institute, University of Manchester Oxford Road Manchester M13 9PL UK.
Brian R SaundersDepartment of Materials, University of Manchester, MSS Tower Manchester M13 9PL UK mingning.zhu@manchester.ac.uk dongdong.lu@manchester.ac.uk brian.saunders@manchester.ac.uk.ORCID https://orcid.org/0000-0003-1410-2967
University of Manchester · GBOrange (Poland) · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near infra-red (NIR) fluorescence is a desirable property for probe particles because such deeply penetrating light enables remote reporting of the local environment in complex surroundings and imaging. Here, two NIR non-radiative energy transfer (NRET) fluorophores (Cy5 and Cy5.5) are coupled to preformed pH-responsive poly(ethylacrylate-methacrylic acid-divinylbenzene) microgel particles (PEA-MAA-5/5.5 MGs) to obtain new NIR fluorescent probes that are cytocompatible and swell strongly. NIR ratiometric photoluminescence (PL) intensity analysis enables reporting of pH-triggered PEA-MAA-5/5.5 MG particle swelling ratios over a very wide range (from 1-90). The dispersions have greatly improved colloidal stability compared to a reference temperature-responsive NIR MG based on poly(

Identifiers

PMID36132786
PMCPMC9419105
OpenAlexW3049501621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.