Evidence map›Paper›PMID 36132503›Full record

ArticleNanoscale advances2020

A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of living stem cell functions according to intracellular temperature.

Hiroshi Yukawa, Masazumi Fujiwara, Kaori Kobayashi, Yuka Kumon, Kazu Miyaji, Yushi Nishimura, Keisuke Oshimi, Yumi Umehara, Yoshio Teki, Takayuki Iwasaki and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Review
  3. High-throughput chip-calorimeter using a BiMicrosystems & nanoengineering · 2025
    Article
  4. Nanobiodevices and quantum life science for future healthcare.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Cellular Thermal Biology Using Fluorescent Nanothermometers.Advances in experimental medicine and biology · 2024
    Article
  11. Optical and electronic spin properties of fluorescent micro- and nanodiamonds upon prolonged ultrahigh-temperature annealing.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Hiroshi YukawaInstitute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University Nagoya Japan h.yukawa@nanobio.nagoya-u.ac.jp babaymtt@chembio.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0002-9352-1520
Masazumi FujiwaraDepartment of Chemistry, Graduate School of Science, Osaka City University Osaka Japan masazumi@osaka-cu.ac.jp.ORCID https://orcid.org/0000-0002-7845-2387
Kaori KobayashiDepartment of Biomolecular Engineering, Graduate School of Engineering, Nagoya University Nagoya Japan.
Yuka KumonDepartment of Biomolecular Engineering, Graduate School of Engineering, Nagoya University Nagoya Japan.
Kazu MiyajiDepartment of Biomolecular Engineering, Graduate School of Engineering, Nagoya University Nagoya Japan.
Yushi NishimuraInstitute of Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology Chiba Japan.
Keisuke OshimiDepartment of Chemistry, Graduate School of Science, Osaka City University Osaka Japan masazumi@osaka-cu.ac.jp.
Yumi UmeharaDepartment of Chemistry, Graduate School of Science, Osaka City University Osaka Japan masazumi@osaka-cu.ac.jp.
Yoshio TekiDepartment of Chemistry, Graduate School of Science, Osaka City University Osaka Japan masazumi@osaka-cu.ac.jp.ORCID https://orcid.org/0000-0003-2906-3382
Takayuki IwasakiDepartment of Electrical and Electronic Engineering, Graduate School of Engineering, Tokyo Institute of Technology Tokyo Japan.
Mutsuko HatanoDepartment of Electrical and Electronic Engineering, Graduate School of Engineering, Tokyo Institute of Technology Tokyo Japan.
Hideki HashimotoSchool of Science and Technology, Kwansei Gakuin University Hyogo Japan.
Yoshinobu BabaInstitute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University Nagoya Japan h.yukawa@nanobio.nagoya-u.ac.jp babaymtt@chembio.nagoya-u.ac.jp.
Osaka City University · JPNagoya University · JPLife Systems (United States) · USTokyo Institute of Technology · JPKwansei Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular thermometry techniques play an important role in elucidating the relationship between the intracellular temperature and stem cell functions. However, there have been few reports on thermometry techniques that can detect the intracellular temperature of cells during several days of incubation. In this study, we developed a novel quantum thermometric sensing and analysis system (QTAS) using fluorescent nanodiamonds (FNDs). FNDs could label adipose tissue-derived stem cells (ASCs) at high efficiency with 24 h of incubation, and no cytotoxicity was observed in ASCs labeled with less than 500 μg mL

Identifiers

PMID36132503
PMCPMC9419001
OpenAlexW3014174057

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.