Evidence map›Paper›PMID 36132469›Full record

ArticleNanoscale advances2019

Sub-picogram level sensitivity in HIV diagnostics achieved with the europium nanoparticle immunoassay through metal enhanced fluorescence.

Aditya Kurdekar, L A Avinash Chunduri, Mohan Kumar Haleyurgirisetty, Indira K Hewlett, Venkataramaniah Kamisetti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aditya KurdekarLaboratories for Nanoscience and Nanotechnology Research, Department of Physics, Sri Sathya Sai Institute of Higher Learning Prasanthi Nilayam Puttaparthi 515134 India vrkamisetti@gmail.com.ORCID https://orcid.org/0000-0002-0704-0633
L A Avinash ChunduriLaboratories for Nanoscience and Nanotechnology Research, Department of Physics, Sri Sathya Sai Institute of Higher Learning Prasanthi Nilayam Puttaparthi 515134 India vrkamisetti@gmail.com.ORCID https://orcid.org/0000-0001-8226-3979
Mohan Kumar HaleyurgirisettyLaboratory of Molecular Virology, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration Silver Spring MD 20993 USA.
Indira K HewlettLaboratory of Molecular Virology, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration Silver Spring MD 20993 USA.
Venkataramaniah KamisettiLaboratories for Nanoscience and Nanotechnology Research, Department of Physics, Sri Sathya Sai Institute of Higher Learning Prasanthi Nilayam Puttaparthi 515134 India vrkamisetti@gmail.com.ORCID https://orcid.org/0000-0002-5706-5919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a novel application of Metal Enhanced Fluorescence (MEF) to immunoassays for boosting the signal through a single step modification of the europium nanoparticle based immunoassay with addition of gold nanoparticles. The new limit of detection was found to be 0.19 pg mL

Identifiers

PMID36132469
PMCPMC9473166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.