Evidence map›Paper›PMID 36132425›Full record

ArticleBrain communications2022

Incidence and prevalence of coma in the UK and the USA.

Daniel Kondziella, Moshgan Amiri, Marwan H Othman, Ettore Beghi, Yelena G Bodien, Giuseppe Citerio, Joseph T Giacino, Stephan A Mayer, Thomas N Lawson, David K Menon and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06426602 (Unlocking Functional Communication for Patients With Disorders of Consciousness With Innovative Brain Computer Interface Technology), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06426602 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Unlocking Functional Communication for Patients With Disorders of Consciousness With Innovative Brain Computer Interface Technology

TypeinterventionalSponsorAmy WagnerRan2024 to 2026Enrolled40ConditionsDisorders of ConsciousnessArmsmindBEAGLE daily device use
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Covert consciousness: what's in a name?Brain : a journal of neurology · 2025
    Article
  12. Review
  13. Observational
  14. The Gray Zone of Consciousness: Cognitive Motor Dissociation.Current neurology and neuroscience reports · 2025
    Review
  15. Review
  16. Article
  17. Covert consciousness in critical care.Intensive care medicine · 2025
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Daniel KondziellaDepartment of Neurology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-5562-9808
Moshgan AmiriDepartment of Neurology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
Marwan H OthmanDepartment of Neurology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
Ettore BeghiDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy.
Yelena G BodienDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA 02115, USA.
Giuseppe CiterioNeuroIntensive Care, ASST di Monza, Monza 20900, Italy.
Joseph T GiacinoDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA 02115, USA.
Stephan A MayerDepartment of Neurology, New York Medical College, Valhalla, NY 10595, USA.
Thomas N LawsonCollege of Nursing, The Ohio State University, Columbus, OH 43210, USA.
David K MenonDivision of Anaesthesia, University of Cambridge, Cambridge CB2 2QQ, UK.ORCID https://orcid.org/0000-0002-3228-9692
Verena RassDepartment of Neurology, Neuro-Intensive Care Unit, Medical University of Innsbruck, Innsbruck 6020, Austria.
Tarek SharsharNeuro-anesthesiology and Intensive Care Medicine, Sainte-Anne Hospital, Paris-Descartes University, Paris 75006, France.
Robert D StevensDepartment of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Lorenzo TintiDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy.
Paul VespaDepartment of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Molly McNettCollege of Nursing, The Ohio State University, Columbus, OH 43210, USA.
Chethan P Venkatasubba RaoDivision of Vascular Neurology and Neurocritical Care, Baylor College of Medicine and CHI Baylor St Luke's Medical Center, Houston, TX 77030, USA.
Raimund HelbokDepartment of Neurology, Neuro-Intensive Care Unit, Medical University of Innsbruck, Innsbruck 6020, Austria.ORCID https://orcid.org/0000-0001-5682-0145
Curing Coma Campaign Collaborators

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
ACL HHS 90DP0039ACL HHS 90DPCP0008NCCDPHP CDC HHS U48 DP000039NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

The epidemiology of coma is unknown because case ascertainment with traditional methods is difficult. Here, we used crowdsourcing methodology to estimate the incidence and prevalence of coma in the UK and the USA. We recruited UK and US laypeople (aged ≥18 years) who were nationally representative (i.e. matched for age, gender and ethnicity according to census data) of the UK and the USA, respectively, utilizing a crowdsourcing platform. We provided a description of coma and asked survey participants if they-'right now' or 'within the last year'-had a family member in coma. These participants (UK

Indexed as

brain injurycardiac arrestcomaconsciousnessCOVID-19

Identifiers

PMID36132425
PMCPMC9486895

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.