ArticleNanoscale advances2020
Enhancing curcumin's solubility and antibiofilm activity
Article in Nanoscale advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 37 citations in OpenAlex.
- Microfluidic-assembled curcumin ionizable lipid nanoparticles enhance aqueous delivery and antibiofilm activity againstInternational journal of pharmaceutics: X · 2026Article
- Synthesis of Modified Silver- or Copper-Loaded Silica Nanocarriers as a Tool for Curcumin Delivery.Nanomaterials (Basel, Switzerland) · 2026Article
- Curcumin-Based Nanoformulations for Oral Health: Mechanistic Insights, Antimicrobial Efficacy, and Future Clinical Perspectives.Biomedicines · 2026Review
- Synthesis and Characterization of Curcumin-Polycaprolactone Block Copolymers for Biomedical Applications.Materials (Basel, Switzerland) · 2025Article
- Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens.Pathogens (Basel, Switzerland) · 2023Review
- A Xanthan-Gum-Stabilized PEG-Conjugated Nanocurcumin Complex: Telescoping Synthesis for Enhanced Permeation Potential.ChemistryOpen · 2023Article
- Modeling the Properties of Curcumin Derivatives in Relation to the Architecture of the Siloxane Host Matrices.Materials (Basel, Switzerland) · 2021Article
- Antimicrobial, Antibiofilm, and Antioxidant Activity of Functional Poly(Butylene Succinate) Films Modified with Curcumin and Carvacrol.Materials (Basel, Switzerland) · 2021Article
- Synthesis and self-assembly of curcumin-modified amphiphilic polymeric micelles with antibacterial activity.Journal of nanobiotechnology · 2021Article
- Curcumin-loaded PEGylated mesoporous silica nanoparticles for effective photodynamic therapy.RSC advances · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial biofilms are microbial communities in which bacterial cells in sessile state are mechanically and chemically protected against foreign agents, thus enhancing antibiotic resistance. The delivery of active compounds to the inside of biofilms is often hindered due to the existence of the biofilm extracellular polymeric substances (EPS) and to the poor solubility of drugs and antibiotics. A possible strategy to overcome the EPS barrier is the incorporation of antimicrobial agents into a nanocarrier, able to penetrate the matrix and deliver the active substance to the cells. Here, we report the synthesis of antimicrobial curcumin-conjugated silica nanoparticles (curc-NPs) as a possibility for dealing with these issues. Curcumin is a known antimicrobial agent and to overcome its low solubility in water it was grafted onto the surface of silica nanoparticles, the latter functioning as nanocarrier for curcumin into the biofilm. Curc-NPs were able to impede the formation of model
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.