Evidence map›Paper›PMID 36132260›Full record

ArticleNanoscale advances2019

Colorimetric sensing strategy for heparin assay based on PDDA-induced aggregation of gold nanoparticles.

Xiaoyi Ma, Xinyue Kou, Yuanyuan Xu, Dawei Yang, Peng Miao

Abstract read
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. TPE-based cationic AIEgen with large stokes shift enables detection of blood anti-coagulator heparin with high selectivity.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Quality Control of Heparin Injections: Comparison of Four Established Methods.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyi MaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Suzhou 215163 P. R. China miaopeng@sibet.ac.cn.
Xinyue KouSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Suzhou 215163 P. R. China miaopeng@sibet.ac.cn.
Yuanyuan XuKey Laboratory of Animal Physiology and Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University Nanjing 210095 P. R. China.
Dawei YangSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Suzhou 215163 P. R. China miaopeng@sibet.ac.cn.
Peng MiaoSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences Suzhou 215163 P. R. China miaopeng@sibet.ac.cn.ORCID https://orcid.org/0000-0003-3993-4778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a highly sensitive colorimetric sensor for the detection of heparin based on its anti-aggregation effect of the PDDA-gold nanoparticle colloidal system. PDDA-induced non-crosslinking aggregation of gold nanoparticles is firstly investigated and the phenomenon of heparin mediated color recovery is then observed, which can be used to indicate the concentration of heparin. This method is proved to be highly sensitive and selective. Moreover, it has been successfully applied to determine human blood serum samples, the results of which demonstrate great potential practical utility with simple operations.

Identifiers

PMID36132260
PMCPMC9473268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.