Evidence map›Paper›PMID 36132237›Full record

ArticleNanoscale advances2019

Carboxymethyl cellulose coated magnetic nanoparticles transport across a human lung microvascular endothelial cell model of the blood-brain barrier.

Gabriela Aguilera, Catherine C Berry, Rachel M West, Enrique Gonzalez-Monterrubio, Aracely Angulo-Molina, Óscar Arias-Carrión, Miguel Ángel Méndez-Rojas

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 109 citations in OpenAlex.

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  10. The blood-brain barrier: structure, regulation, and drug delivery.Signal transduction and targeted therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Gabriela AguileraDepartamento de Ciencias Químico-Biológicas, Universidad de las Américas Puebla Ex Hda. Sta. Catarina Mártir s/n, San Andrés Cholula 72820 Puebla Mexico miguela.mendez@udlap.mx +52 222 2292416 +52 222 2292607.
Catherine C BerryCentre for Cell Engineering, Institute of Molecular Cell and Systems Biology, University of Glasgow Joseph Black Building, University Avenue Glasgow Scotland.
Rachel M WestDepartamento de Ciencias Químico-Biológicas, Universidad de las Américas Puebla Ex Hda. Sta. Catarina Mártir s/n, San Andrés Cholula 72820 Puebla Mexico miguela.mendez@udlap.mx +52 222 2292416 +52 222 2292607.ORCID https://orcid.org/0000-0003-2112-657X
Enrique Gonzalez-MonterrubioDepartamento de Ciencias Químico-Biológicas, Universidad de las Américas Puebla Ex Hda. Sta. Catarina Mártir s/n, San Andrés Cholula 72820 Puebla Mexico miguela.mendez@udlap.mx +52 222 2292416 +52 222 2292607.
Aracely Angulo-MolinaDepartamento de Ciencias Químico-Biológicas/DIFUS, Universidad de Sonora Luis Encinas y Rosales, s/n Colonia Centro, 83000 Hermosillo Sonora Mexico.ORCID https://orcid.org/0000-0002-8586-3387
Óscar Arias-CarriónUnidad de Trastornos del Movimiento y Sueño (TMS), Hospital General Dr Manuel Gea González Av. Calzada de Tlalpan 4800, Col. Sección XVI C. P. 14080 Mexico City Mexico arias@ciencias.unam.mx +52 55 52115199 +52 155 26849064.ORCID https://orcid.org/0000-0002-9982-7571
Miguel Ángel Méndez-RojasDepartamento de Ciencias Químico-Biológicas, Universidad de las Américas Puebla Ex Hda. Sta. Catarina Mártir s/n, San Andrés Cholula 72820 Puebla Mexico miguela.mendez@udlap.mx +52 222 2292416 +52 222 2292607.ORCID https://orcid.org/0000-0002-4758-3763
Universidad de las Américas Puebla · MXAyuntamiento de Sevilla · ESGlasgow Life · GBUniversidad de Sonora · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustained and safe delivery of therapeutic agents across the blood-brain barrier (BBB) is one of the major challenges for the treatment of neurological disorders as this barrier limits the ability of most drug molecules to reach the brain. Targeted delivery of the drugs used to treat these disorders could potentially offer a considerable reduction of the common side effects of their treatment. The preparation and characterization of carboxymethyl cellulose (CMC) coated magnetic nanoparticles (Fe

Identifiers

PMID36132237
PMCPMC9473188
OpenAlexW2896059061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.