Evidence map›Paper›PMID 36132225›Full record

ReviewOxidative medicine and cellular longevity2022

Understanding the Protective Role of Exosomes in Doxorubicin-Induced Cardiotoxicity.

Guoxia Zhang, Xinyu Yang, Xin Su, Na An, Fan Yang, Xinye Li, Yuchen Jiang, Yanwei Xing

Abstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Sarmentosin alleviates doxorubicin-induced cardiotoxicity and ferroptosisRedox report : communications in free radical research · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guoxia ZhangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0003-0646-8758
Xinyu YangFangshan Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Xin SuGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-5764-4355
Na AnBeijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0001-7794-2539
Fan YangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-8181-1627
Xinye LiBeijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0001-8131-4981
Yuchen JiangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0003-4660-7847
Yanwei XingGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-1392-9738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (DOX) is a class of effective chemotherapeutic agents widely used in clinical practice. However, its use has been limited by cardiotoxicity. The mechanism of DOX-induced cardiotoxicity (DIC) is complex, involving oxidative stress, Ca

Indexed as

CardiotoxicityExosomesApoptosisBiomarkersDoxorubicinHumansMyocytes, CardiacOxidative StressBiomarkersDoxorubicin

Identifiers

PMID36132225
PMCPMC9484956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.