Evidence map›Paper›PMID 36132154›Full record

ReviewFrontiers in oncology2022

Research progress on the mechanism of radiation enteritis.

Jinjia Fan, Binwei Lin, Mi Fan, Tintin Niu, Feng Gao, Bangxian Tan, Xiaobo Du

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05749484 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prediction of the Chronicization of Radiation-induced Acute Intestinal Injury Based on the Expression Level of Immune Factors: a Prospective, Observational and Confirmatory Clinical Study

TypeobservationalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2023 to 2026Enrolled200ConditionsRadiation-induced Intestinal InjuryArmsNCRT+TME
NCT05749497 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prediction of the Chronicization of Radiation-induced Acute Intestinal Injury Based on the Expression Level of lncRNA: a Prospective, Observational and Confirmatory Clinical Study

TypeobservationalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2023 to 2026Enrolled200ConditionsRadiation-induced Intestinal InjuryArmsNCRT+TME
NCT05749510 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prediction of Radiation-induced Acute Intestinal Injury Based on the Phase Separation Level of DNA Repair Factors: a Prospective, Observational and Confirmatory Clinical Study

TypeobservationalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2023 to 2026Enrolled200ConditionsRadiation-induced Intestinal InjuryArmsNCRT+TME
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Gut microbes · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Distinct molecular responses of human intestinal organoids to proton and photon radiation.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Food science & nutrition · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. [Effects of Ionizing Radiation on Intestinal Bile Acid Metabolism: Mechanism of the Radioprotective Effect of Glycoursodeoxycholic Acid].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jinjia FanDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Binwei LinDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Mi FanDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Tintin NiuDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Feng GaoDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Bangxian TanDepartment of Oncology, Affiliated Hospital of North Sichuan Medical College, Nan Chong, China.
Xiaobo DuDepartmant of Oncology, National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology, Mianyang, China.
Mianyang Central Hospital · CNAffiliated Hospital of North Sichuan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation enteritis (Re) is one of the most common complications of radiation therapy for abdominal tumors. The efficacy of cancer treatment by radiation is often limited by the side effects of Re. Re can be acute or chronic. Treatment of acute Re is essentially symptomatic. However, chronic Re usually requires surgical procedures. The underlying mechanisms of Re are complex and have not yet been elucidated. The purpose of this review is to provide an overview of the pathogenesis of Re. We reviewed the role of intestinal epithelial cells, intestinal stem cells (ISCs), vascular endothelial cells (ECs), intestinal microflora, and other mediators of Re, noting that a better understanding of the pathogenesis of Re may lead to better treatment modalities.

Indexed as

intestinal epithelial cellsintestinal microfloraintestinal stem cellsmechanismRadiation enteritisvascular endothelial cell

Identifiers

PMID36132154
PMCPMC9483210
OpenAlexW4294617880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.