Evidence map›Paper›PMID 36131940›Full record

ArticleFrontiers in immunology2022

Severe aplastic anemia patients with infection who received an allogeneic hematopoietic stem cell transplantation had a better chance: Long-term outcomes of a multicenter study.

Limin Liu, Miao Miao, Hailong He, Shunqing Wang, Yanming Zhang, Ailian Guo, Wenjing Jiao, Meiqing Lei, Yifeng Cai, Xiaohui Shangguan and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 1 country.

Limin LiuNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Miao MiaoNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hailong HeDepartment of Hematology, Children's Hospital of Soochow University, Suzhou, China.
Shunqing WangDepartment of Hematology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Yanming ZhangDepartment of Hematology, The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an, Huai'an, China.
Ailian GuoDepartment of Hematology, Children's Hospital of Soochow University, Suzhou, China.
Wenjing JiaoDepartment of Hematology, Xian Yang Central Hospital, Xianyang, China.
Meiqing LeiDepartment of Hematology in Haikou Municipal People's Hospital, Affiliated Haikou Hospital, Haikou, China.
Yifeng CaiDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, China.
Xiaohui ShangguanDepartment of Hematology, Longyan First Hospital, Affiliated to Fujian Medical University, Longyan, China.
Zefa LiuDepartment of Hematology, People Hospital of Xinghua, Xinghua, China.
Jinge XuDepartment of Hematology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xiaoli LiDepartment of Hematology, Soochow Hopes Hematonosis Hospital, Suzhou, China.
Liansheng ZhangDepartment of Hematology, The Second Hospital of Lanzhou University, Lanzhou, China.
Depei WuNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNAffiliated Hospital of Nantong University · CNFirst Affiliated Hospital of Fujian Medical University · CNGuangzhou Medical University · CNHaikou City People's Hospital · CNLanzhou University · CNSecond People’s Hospital of Huai’an · CNXian Yang Central Hospital · CNXintai People's Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: How to select the treatment is a challenge for the management of acquired patients with infections. This study aimed at comparing the outcomes of SAA with infections who had an allogeneic hematopoietic stem cell transplantation (allo-HSCT)with that of patients who had an infection and received non-HSCT therapy. Methods: We retrospectively compared the outcomes of patients with acquired SAA and infections who had an allo-HSCT ( Results: The treatment-related mortality (TRM) of grade 1-2 infections in the HSCT and non-HSCT groups was 24.99% and 13.68%, respectively ( Conclusion: These results suggest that allo-HSCT has a better chance of a successful outcome than non-HSCT in SAA patients with an infection.

Indexed as

Anemia, AplasticGraft vs Host DiseaseHematopoietic Stem Cell TransplantationLymphoma, FollicularHumansRetrospective StudiesTreatment Outcomeallogeneic hematopoietic stem cell transplantationinfectionresultsSevere aplastic anemiatherapy

Identifiers

PMID36131940
PMCPMC9483095
OpenAlexW4294628182

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.