Evidence map›Paper›PMID 36131298›Full record

ArticleActa neuropathologica communications2022

Letter to the editor on a paper by Kaivola et al. (2020): carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is not associated with amyotrophic lateral sclerosis or frontotemporal dementia.

Sterre C M de Boer, Lauren Woolley, Merel O Mol, Maria Serpente, Lianne M Reus, Rick van Minkelen, Joke F A van Vugt, Federica Sorrentino, Jan H Veldink, Harro Seelaar and 6 more

Open access · goldAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Distribution of theFrontiers in neurology · 2024
    Article
  3. Frontiers in genetics · 2023
    Article
  4. Response to the letter by de Boer et al. (2022).Acta neuropathologica communications · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 5 countries.

Sterre C M de BoerAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands. scm.deboer@amsterdamumc.nl.ORCID 0000-0002-9595-7221
Lauren WoolleyMRC Prion Unit at UCL, Institute of Prion Diseases, UCL, London, UK.
Merel O MolDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Maria SerpenteFoundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Lianne M ReusAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Rick van MinkelenDepartment of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Joke F A van VugtDepartment of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Federica SorrentinoFoundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Jan H VeldinkDepartment of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Harro SeelaarDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Daniela GalimbertiFoundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Fred van RuissenDepartment of Human Genetics, Amsterdam Reproduction and Development Research Institute, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Simon MeadMRC Prion Unit at UCL, Institute of Prion Diseases, UCL, London, UK.
Ekaterina RogaevaTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.
Yolande A L PijnenburgAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Sven J van der LeeAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Amsterdam Neuroscience · NLErasmus MC · NLMRC Prion Unit · GBUniversity of Milan · ITUtrecht University · NLFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Amsterdam · NLUniversity of California, Los Angeles · USUniversity of Toronto · CA

Funding

Medical Research Council MC_UU_00024/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyotrophic Lateral SclerosisFrontotemporal DementiaPick Disease of the BrainAllelesC9orf72 ProteinDNA Repeat ExpansionFinlandHumansRisk FactorsC9orf72 ProteinC9orf72 protein, human

Identifiers

PMID36131298
PMCPMC9494883
OpenAlexW4296793867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.