Evidence map›Paper›PMID 36131014›Full record

ArticleNature2022

Failure of human rhombic lip differentiation underlies medulloblastoma formation.

Liam D Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H Sjoboen, Anders W Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L Mercier and 123 more

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it, 154 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. From developmental origins to relapse: molecular and therapeutic insights in medulloblastoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Developmental determinants of male bias in medulloblastoma.bioRxiv : the preprint server for biology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Spatiotemporal histogenesis of the developing human cerebellum reveals dynamic layering of Bergmann glia.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

133 authors at 20 institutions in 18 countries.

Liam D Hendrikse *The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-0253-8512
Parthiv Haldipur *Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Olivier Saulnier *The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-4111-1017
Jake MillmanCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Alexandria H SjoboenCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Anders W EricksonThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-6134-7812
Winnie OngThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Victor GordonDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Ludivine Coudière-MorrisonDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Audrey L MercierPSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France.
Mohammad ShokouhianDepartment of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0001-5061-7058
Raúl A SuárezThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Michelle LyThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Stephanie BorlaseDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
David S ScottThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Maria C VladoiuThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Hamza FarooqThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Olga SirbuThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Takuma NakashimaDivision of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.ORCID http://orcid.org/0000-0002-5198-3516
Shohei NambuDivision of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Yusuke FunakoshiDivision of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Alec BahcheliDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
J Javier Diaz-MejiaPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-2475-3077
Joseph GolserCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Kathleen BachCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Tram Phuong-BaoDepartment of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Patryk SkowronThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Evan Y WangThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7984-3147
Sachin A KumarThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-4853-3864
Polina BalinThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Abhirami VisvanathanThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
John J Y LeeThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ramy AyoubDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7099-9284
Xin ChenThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7620-5975
Xiaodi ChenThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Karen L MungallCanada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Betty LuuThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pierre BérubéMcGill University Genome Centre, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-1008-192X
Yu C WangMcGill University Genome Centre, McGill University, Montreal, Quebec, Canada.
Stefan M PfisterDivision of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5447-5322
Seung-Ki KimDepartment of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea.
Olivier DelattreSIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.ORCID http://orcid.org/0000-0002-8730-2276
Franck BourdeautSIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.
François DozSIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.
Julien Masliah-PlanchonUnit of Somatic Genetics, Institut Curie, Paris, France.
Wieslawa A GrajkowskaDepartment of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.
James LoukidesThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Peter DirksThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-5718-6465
Michelle Fèvre-MontangeINSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences, Université de Lyon, Lyon, France.
Anne JouvetCentre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France.
Pim J FrenchDepartment of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0002-0668-9529
Johan M KrosDepartment of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands.
Karel ZitterbartDepartment of Pediatric Oncology, Masaryk University School of Medicine, Brno, Czech Republic.
Swneke D BaileyDepartment of Surgery, Division of Thoracic and Upper Gastrointestinal Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
Charles G EberhartDepartments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, USA.
Amulya A N RaoDivision of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA.
Caterina GianniniDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0003-2757-6782
James M OlsonClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-5990-6534
Miklós Garami2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0003-4298-2746
Peter Hauser2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Joanna J PhillipsDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-3789-8120
Young S RaDepartment of Neurosurgery, University of Ulsan, Asan Medical Center, Seoul, South Korea.
Carmen de TorresDevelopmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Jaume MoraDevelopmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Kay K W LiDepartment of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Ho-Keung NgDepartment of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Wai S PoonDepartment of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong.
Ian F PollackDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Enrique López-AguilarDivision of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional century XXI, Mexico City, Mexico.
G Yancey GillespieDepartment of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Timothy E Van MeterPediatrics, Virginia Commonwealthy University, School of Medicine, Richmond, VA, USA.
Tomoko ShofudaDivision of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan.
Rajeev VibhakarDepartment of Pediatrics, University of Colorado Denver, Aurora, CO, USA.ORCID http://orcid.org/0000-0002-5949-3896
Reid C ThompsonDepartment of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA.
Michael K CooperDepartment of Neurology, Vanderbilt Medical Center, Nashville, TN, USA.
Joshua B RubinDepartments of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-7395-1937
Toshihiro KumabeDepartment of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan.
Shin JungDepartment of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, South Korea.
Boleslaw LachDepartment of Pathology and Molecular Medicine, Division of Anatomical Pathology, McMaster University, Hamilton, Ontario, Canada.
Achille IolasconDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.
Veronica FerrucciDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.
Pasqualino de AntonellisDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.
Massimo ZolloDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.ORCID http://orcid.org/0000-0002-0970-7243
Giuseppe CinalliDepartment of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Shenandoah RobinsonDivision of Pediatric Neurosurgery, Case Western Reserve, Cleveland, OH, USA.
Duncan S StearnsDepartment of Pediatrics-Hematology and Oncology, Case Western Reserve, Cleveland, OH, USA.
Erwin G Van MeirDepartment of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
Paola PorratiFondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Gaetano FinocchiaroFondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Maura MassiminoFondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Carlos G CarlottiDepartment of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
Claudia C FariaDivision of Neurosurgery, Centro Hospitalar Lisboa Norte (CHULN), Hospital de Santa Maria, Lisbon, Portugal.
Martine F RousselDepartment of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-1740-8139
Frederick BoopDepartment of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA.
Jennifer A ChanCharbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.
Kimberly A AldingerCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5406-8911
Ferechte RazaviAssistance Publique Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris, France.
Evelina SilvestriSurgical Pathology Unit, San Camillo Forlanini Hospital, Rome, Italy.
Roger E McLendonDepartment of Pathology, Duke University, Durham, NC, USA.
Eric M ThompsonDepartment of Neurosurgery, Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0003-2796-9914
Marc AnsariCansearch Research Platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.
Maria L GarreU.O. Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy.
Fernando ChicoDepartment of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.
Pilar EguíaDepartment of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.ORCID http://orcid.org/0000-0003-0385-8902
Mario PérezpeñaInstituto Nacional De Pediatría de México, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-1007-7744
A Sorana MorrissyCharbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.
Florence M G CavalliINSERM U900, Institut Curie, Paris, France.
Xiaochong WuThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Craig DanielsThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jeremy N RichUPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Steven J M JonesCanada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0003-3394-2208
Richard A MooreCanada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Marco A MarraCanada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0001-7146-7175
Xi HuangThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-7177-7525
Jüri ReimandDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-2299-2309
Poul H SorensenDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Robert J Wechsler-ReyaTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-7463-8352
William A WeissDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Trevor J PughDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Livia GarziaCancer Research Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada.
Claudia L KleinmanDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-5158-7126
Lincoln D SteinDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Nada JabadoDepartments of Pediatrics and Human Genetics, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-2485-3692
David MalkinDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-5752-9763
Olivier AyraultPSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France.ORCID http://orcid.org/0000-0002-7942-6674
Jeffrey A GoldenDepartment of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
David W EllisonDepartment of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
Brad DobleDepartment of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0002-0260-2983
Vijay RamaswamyThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-6557-895X
Tamra E Werbowetski-OgilvieDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0002-5469-0559
Hiromichi SuzukiDivision of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.ORCID http://orcid.org/0000-0002-8858-0294
Kathleen J MillenCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9978-675X
Michael D TaylorThe Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. mdt.cns@gmail.com.
University of Toronto · CAHospital for Sick Children · CAUniversity of Manitoba · CABC Cancer Agency · CACeinge Biotecnologie Avanzate (Italy) · ITOntario Institute for Cancer Research · CAChinese University of Hong Kong · HKFondazione IRCCS Istituto Nazionale dei Tumori · ITInserm · FRMcGill University Health Centre · CASt. Jude Children's Research Hospital · USCase Western Reserve University · USDuke University · USErasmus MC · NLHospital Infantil de México Federico Gómez · MXHospital Sant Joan de Déu Barcelona · ESMayo Clinic in Arizona · USMcGill Genome Centre · CASemmelweis University · HUUniversité Claude Bernard Lyon 1 · FR

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
The DNA Damage Response and Tumorigenesis in the BrainP01CA096832 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BAKER, SUZANNE J. · 2003 to 2025
$38.0M
Shared Resources Core 2: Quantitative Proteomics CoreP01CA196539 · NCI · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2015 to 2024
$17.6M
Mouse models to discover new drivers of medulloblastomaR01CA159859 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Michael D. Taylor, WILLIAM A WEISS · 2011 to 2026
$10.4M
Pathological Mechanisms of Human Cerebellar MalformationsR37NS095733 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI Kathleen Joyce Millen · 2021 to 2026
$5.5M
CCL2 and CCR2 as metastatic drivers and therapeutic targets in medulloblastomaR01CA255369 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARZIA, LIVIA, TAYLOR, MICHAEL D. · 2021 to 2025
$3.9M
A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human CerebellumR01NS122902 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI Mary Elizabeth Hatten, Kathleen Joyce Millen · 2022 to 2026
$3.3M
Pathological Mechanisms of Human Cerebeller MalformationsR01NS095733 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2016 to 2020
$3.0M
Prevention and treatment of lethal metastases in group 3 medulloblastomaR01NS106155 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TAYLOR, MICHAEL D., WEISS, WILLIAM A · 2018 to 2022
$2.8M
Precision models of ARX-associated neurodevelopmental disordersR01NS113516 · NINDS · UNIVERSITY OF TEXAS SAN ANTONIO · PI GOLDEN, JEFFREY A, HSIEH, JENNY · 2019 to 2023
$2.6M
Congenital brain malformations caused by aberrant head mesenchymal signalingR01NS080390 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2012 to 2016
$2.3M
Evaluating ADGRB3 as a tumor suppressor epigenetically silenced in WNT medulloblastomaR01CA235162 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VAN MEIR, ERWIN G. · 2019 to 2024
$2.3M
Medical Research Council MR/R006237/1NCI NIH HHS P01 CA096832NCI NIH HHS P01 CA196539NCI NIH HHS P30 CA014236NCI NIH HHS R01 CA159859NCI NIH HHS R01 CA235162NCI NIH HHS R01 CA255369NINDS NIH HHS R01 NS080390NINDS NIH HHS R01 NS095733NINDS NIH HHS R01 NS106155NINDS NIH HHS R01 NS113516NINDS NIH HHS R01 NS122902NINDS NIH HHS R21 NS117848NINDS NIH HHS R37 NS095733
6 · The paper itself

Abstract

Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain

Indexed as

Cell DifferentiationCerebellar NeoplasmsMedulloblastomaMetencephalonCell LineageCerebellumCore Binding Factor alpha SubunitsHedgehog ProteinsHistone DemethylasesHumansKi-67 AntigenMuscle ProteinsMutationOtx Transcription FactorsRepressor ProteinsT-Box Domain ProteinsCBFA2T2 myeloid-transforming gene-related proteinCBFA2T3 protein, humancore binding factor alphaCore Binding Factor alpha SubunitsEOMES protein, humanHedgehog ProteinsHistone DemethylasesKDM6A protein, humanKi-67 AntigenMuscle ProteinsOTX2 protein, humanOtx Transcription FactorsPRDM6 protein, humanRepressor ProteinsT-Box Domain ProteinsTranscription Factors

Identifiers

PMID36131014
PMCPMC10026724
OpenAlexW4296691527

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.