ArticleNature communications2022
A de novo matrix for macroscopic living materials from bacteria.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- De Novo Autogenic Engineered Living Functional Materials.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Soft, Reactive, and Alive: A Dynamic Framework for Degradation and Functional Stability of Polymeric Biomaterials.Polymers · 2026Review
- A programmable fungal platform for engineered living textiles.Science advances · 2026Article
- A programmable living force sensor fabricated with surface engineered microbial network.Nature communications · 2026Article
- Self-Growing and Mechanically Tunable Living Materials withACS applied polymer materials · 2026Article
- Programable and Spatially Conforming Assembly of Engineered Living Materials Onto Electrodes via Redox.Small science · 2026Article
- De Novo Engineered Living Materials via Elastin-Like Polypeptide-Mediated Self-Assembly.ACS synthetic biology · 2026Article
- Light-based 3D printing of mechanoluminescent living gels loaded with dinoflagellates.Science advances · 2026Article
- Optimizing genetic engineering approaches for protein loading into bacterial extracellular vesicles for vaginal drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- Programming cellular condensates for living materials using an intrinsically disordered protein display platform.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Bacterial Species in Engineered Living Materials: Strategies and Future Directions.Microbial biotechnology · 2025Review
- Living Porous Ceramics for Bacteria-Regulated Gas Sensing and Carbon Capture.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Cohesive Living Bacterial Films with Tunable Mechanical Properties from Cell Surface Protein Display.ACS synthetic biology · 2024Article
- Macroscopic Assembly of Materials with Engineered Bacterial Spores via Coiled-Coil Interaction.ACS synthetic biology · 2024Article
- Mechanically Tunable, Compostable, Healable and Scalable Engineered Living Materials.Nature communications · 2024Article
- Transcriptional regulation of living materials via extracellular electron transfer.Nature chemical biology · 2024Article
- Directed evolution of material-producing microorganisms.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Synthetic microbiology in sustainability applications.Nature reviews. Microbiology · 2024Review
- Fabrication of Living Entangled Network Composites Enabled by Mycelium.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Cell-Free Protein Expression in Polymer Materials.ACS synthetic biology · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Engineered living materials (ELMs) embed living cells in a biopolymer matrix to create materials with tailored functions. While bottom-up assembly of macroscopic ELMs with a de novo matrix would offer the greatest control over material properties, we lack the ability to genetically encode a protein matrix that leads to collective self-organization. Here we report growth of ELMs from Caulobacter crescentus cells that display and secrete a self-interacting protein. This protein formed a de novo matrix and assembled cells into centimeter-scale ELMs. Discovery of design and assembly principles allowed us to tune the composition, mechanical properties, and catalytic function of these ELMs. This work provides genetic tools, design and assembly rules, and a platform for growing ELMs with control over both matrix and cellular structure and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.