Evidence map›Paper›PMID 36130887›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Becker Muscular Dystrophy Accompanied by Anti-HMGCR Antibody-positive Immune-mediated Necrotizing Myopathy.

Asami Munekane, Yutaka Ohsawa, Mariko Okubo, Taiji Nagai, Hirotake Nishimura, Ichizo Nishino, Yoshihide Sunada

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Asami MunekaneDepartment of Neurology, Kawasaki Medical School, Japan.
Yutaka OhsawaDepartment of Neurology, Kawasaki Medical School, Japan.
Mariko OkuboDepartment of Neuromuscular Research, National Institute of Neuroscience (NCNP), Japan.
Taiji NagaiDepartment of Neurology, Kawasaki Medical School, Japan.
Hirotake NishimuraDepartment of Pathology, Kawasaki Medical School, Japan.
Ichizo NishinoDepartment of Neuromuscular Research, National Institute of Neuroscience (NCNP), Japan.
Yoshihide SunadaDepartment of Neurology, Kawasaki Medical School, Japan.
Kawasaki Medical School · JPNational Center of Neurology and Psychiatry · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Becker muscular dystrophy (BMD) is an X-linked neuromuscular disease characterized by progressive muscle weakness that currently has no cure. Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune inflammatory myopathy characterized by proximal muscle weakness that is treated with immunosuppressive therapy. We herein report a patient diagnosed with BMD complicated with IMNM by a pathological analysis. Notably, the patient had an elevated serum anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody level. Oral glucocorticoid and methotrexate treatment partially improved the muscle weakness with decreased levels of serum creatine kinase. An accurate diagnosis is important for therapeutic decisions in these complicated cases.

Indexed as

Autoimmune DiseasesMuscular DiseasesMuscular Dystrophy, DuchenneMyositisAutoantibodiesHumansHydroxymethylglutaryl CoA ReductasesMuscle WeaknessNecrosisAutoantibodiesHMGCR protein, humanHydroxymethylglutaryl CoA Reductasesanti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodyBecker muscular dystrophyimmune-mediated necrotizing myopathy

Identifiers

PMID36130887
PMCPMC10208778
OpenAlexW4296473247

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.