Evidence map›Paper›PMID 36130765›Full record

ArticleBMJ open2022

Dual mobility versus conventional total hip arthroplasty in femoral neck fractures (DISTINCT): protocol for a registry-nested, open-label, cluster-randomised crossover trial.

John E Farey, Tamara Hooper, Tania Alland, Justine M Naylor, Thu-Lan Kelly, Michelle Lorimer, Adriane M Lewin, Margaret Rogers, Chi Kin Law, Jacqueline Close and 5 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

John E FareyInstitute for Musculoskeletal Health, King George V Building, Royal Prince Alfred Hospital, The University of Sydney, Sydney, New South Wales, Australia jfar9860@uni.sydney.edu.au.ORCID 0000-0001-5983-7006
Tamara HooperAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Tania AllandAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Justine M NaylorDISTINCT Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Liverpool, New South Wales, Australia.
Thu-Lan KellyClinical and Health Sciences Academic Unit, University of South Australia, Adelaide, South Australia, Australia.
Michelle LorimerSouth Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Adriane M LewinDISTINCT Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Liverpool, New South Wales, Australia.ORCID 0000-0001-6258-3692
Margaret RogersUniversity of New South Wales - St George Campus, Sydney, New South Wales, Australia.
Chi Kin LawClinical Trials Centre, National Health and Medical Research Council, University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-2364-324X
Jacqueline ClosePrince of Wales Clinical School, University of New South Wales, Randwick, New South Wales, Australia.
Steven E GravesAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Richard S de SteigerAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Peter L LewisAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Sam AdieDISTINCT Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Liverpool, New South Wales, Australia.
Ian A HarrisAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
UNSW Sydney · AUAustralian Orthopaedic Association · AUThe University of Sydney · AUSouth Australian Health and Medical Research Institute · AUThe University of Melbourne · AUUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHip fractures treated with total hip arthroplasty (THA) are at high risk of prosthesis instability, and dislocation is the most common indication for revision surgery. This study aims to determine whether dual mobility THA implants reduce the risk of dislocation compared with conventional THA in patients with hip fracture suitable to be treated with THA. METHODS AND ANALYSIS: This is a cluster-randomised, crossover, open-label trial nested within the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR). The clusters will comprise hospitals that perform at least 12 THAs for hip fracture per annum. All adults age ≥50 years who meet the Australian and New Zealand Hip Fracture Registry guidelines for THA will be included. The intervention will be dual mobility THA and the comparator will be conventional THA. Each hospital will be allocated to two consecutive periods, one of dual mobility THA and the other of conventional THA in random order, aiming for an average of 16 patients eligible for the primary analysis per group (32 total per site), allowing different recruitment totals between sites. Data will be collected through the AOANJRR and linked with patient-level discharge data acquired through government agencies. The primary outcome is dislocation within 1 year. Secondary outcomes include revision surgery for dislocation and all-cause, complications and mortality at 1, 2 and 5 years. If dual mobility THA is found to be superior, a cost-effectiveness analysis will be conducted. The study will aim to recruit 1536 patients from at least 48 hospitals over 3 years. ETHICS AND DISSEMINATION: Ethics approval has been granted (Sydney Local Health District - Royal Prince Alfred Hospital Zone (approval X20-0162 and 2020/ETH00680) and site-specific approvals). Participant recruitment is via an opt-out consent process as both treatments are considered accepted, standard practice. The trial is endorsed by the Australia and New Zealand Musculoskeletal Clinical Trials Network. TRIAL REGISTRATION NUMBER: ACTRN12621000069853.

Indexed as

Arthroplasty, Replacement, HipFemoral Neck FracturesHip FracturesHip ProsthesisAdultAustraliaCross-Over StudiesHumansMiddle AgedProsthesis DesignProsthesis FailureRandomized Controlled Trials as TopicRegistriesReoperationAdult orthopaedicsAnaesthesia in orthopaedicsGERIATRIC MEDICINEHipTrauma management

Identifiers

PMID36130765
PMCPMC9494585
OpenAlexW4296564644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.