Evidence map›Paper›PMID 36130407›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2023

Geostatistical modelling of the distribution, risk and burden of podoconiosis in Kenya.

Kebede Deribe, Hadley Matendechero Sultani, Collins Okoyo, Wyckliff P Omondi, Isaac Ngere, Melanie J Newport, Jorge Cano

Abstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kebede DeribeChildren's Investment Fund Foundation, Addis Ababa, Ethiopia.ORCID 0000-0002-8526-6996
Hadley Matendechero SultaniKenya National Public Health Institute, Nairobi, Kenya.
Collins OkoyoEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya.
Wyckliff P OmondiDivision of Vector Borne and Neglected Tropical Diseases, Ministry of Health, Nairobi, Kenya.
Isaac NgereGlobal Health Program, Washington State University, Nairobi, Kenya.
Melanie J NewportBrighton and Sussex Centre for Global Health Research, Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, UK.ORCID 0000-0002-8946-7525
Jorge CanoExpanded Special Project for Elimination of Neglected Tropical Diseases, World Health Organization Regional Office for Africa, Brazzaville, Republic of the Congo.

Funding

Wellcome Trust 201900Wellcome Trust 201900/Z/16/ZWorld Health Organization 001
6 · The paper itself

Abstract

backgroundUnderstanding and accurately predicting the environmental limits, population at risk and burden of podoconiosis are critical for delivering targeted and equitable prevention and treatment services, planning control and elimination programs and implementing tailored case finding and surveillance activities.

methodsThis is secondary analysis of a nationwide podoconiosis mapping survey in Kenya. We combined national representative prevalence survey data of podoconiosis with climate and environmental data, overlayed with population figures in a geostatistical modelling framework, to predict the environmental suitability, population living in at-risk areas and number of cases of podoconiosis in Kenya.

resultsIn 2020, the number of people living with podoconiosis in Kenya was estimated to be 9344 (95% uncertainty interval 4222 to 17 962). The distribution of podoconiosis varies by geography and three regions (Eastern, Nyanza and Western) represent >90% of the absolute number of cases. High environmental suitability for podoconiosis was predicted in four regions of Kenya (Coastal, Eastern, Nyanza and Western). In total, 2.2 million people live in at-risk areas and 4.2% of the total landmass of Kenya is environmentally predisposed for podoconiosis.

conclusionsThe burden of podoconiosis is relatively low in Kenya and is mostly restricted to certain small geographical areas. Our results will help guide targeted prevention and treatment approaches through local planning, spatial targeting and tailored surveillance activities.

Indexed as

ElephantiasisEnvironmentGeographyHumansKenyaPrevalencegeostatistical modelling, Kenyapodoconiosisriskspatial analysis

Identifiers

PMID36130407
PMCPMC9890307

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.