Evidence map›Paper›PMID 36130019›Full record

ArticleScience translational medicine2022

Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device.

Armen A Gharibans, Stefan Calder, Chris Varghese, Stephen Waite, Gabriel Schamberg, Charlotte Daker, Peng Du, Saeed Alighaleh, Daniel Carson, Jonathan Woodhead and 4 more

3 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 51 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 4 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06401746 recruitingnot on this mapstarted 2024, after this paper: background citation

Assessment of Gastric Function Using Body Surface Gastric Mapping in Patients on Semaglutide (Ozempic)

TypeobservationalSponsorUniversity of Western SydneyRan2024 to 2025Enrolled15ConditionsSemaglutide-Induced Gastric Motility, GastroparesisArmsGastric Alimetry
NCT06411574 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparing the Impact of Body Surface Gastric Mapping and Gastric Emptying Scintigraphy on Clinical Management in Suspected Gastroparesis

TypeinterventionalSponsorUniversity of Western SydneyRan2024 to 2026Enrolled40ConditionsGastroparesisArmsGastric Alimetry
NCT06854120 recruitingnot on this mapstarted 2025, after this paper: background citation

Body Surface Gastric Mapping in Patients With Dyspeptic Symptoms: Recordings at Baseline and on Medical Therapy

TypeobservationalSponsorUniversity of Auckland, New ZealandRan2025 to 2028Enrolled125ConditionsGastroparesis, Functional DyspepsiaArmsGastric Alimetry
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 4 syntheses or guidelines pooled it, 102 citations in OpenAlex.

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  5. Gastric slow-wave morphology in health and disease.Digestive diseases and sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Armen A GharibansSurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-9139-4740
Stefan CalderSurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-5855-1732
Chris VargheseSurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0001-7369-8639
Stephen WaiteAlimetry Ltd., Auckland 1010, New Zealand.
Gabriel SchambergAlimetry Ltd., Auckland 1010, New Zealand.ORCID 0000-0002-4188-9614
Charlotte DakerDepartment of Gastroenterology, North Shore Hospital, Auckland 0620, New Zealand.ORCID 0000-0001-5218-5973
Peng DuAlimetry Ltd., Auckland 1010, New Zealand.
Saeed AlighalehAlimetry Ltd., Auckland 1010, New Zealand.ORCID 0000-0002-8442-143X
Daniel CarsonSurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-5089-2807
Jonathan WoodheadAlimetry Ltd., Auckland 1010, New Zealand.
Gianrico FarrugiaMayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0003-3473-5235
John A WindsorSurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.
Christopher N AndrewsDivision of Gastroenterology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Greg O'GradySurgical and Translational Research Centre, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-5998-1080
University of Auckland · NZAuckland Institute of Studies · NZMayo Clinic in Arizona · USNorth Shore Hospital · NZUniversity of Calgary · CA

Funding

CALCIUM DYNAMICS IN INTERSTITIAL CELLS OF CAJALR01DK057061 · NIDDK · MAYO CLINIC ROCHESTER · PI GIANRICO FARRUGIA, Tamas Ordog · 2000 to 2026
$8.2M
NIDDK NIH HHS R01 DK057061
6 · The paper itself

Abstract

Chronic nausea and vomiting syndromes (NVSs) are prevalent and debilitating disorders. Putative mechanisms include gastric neuromuscular disease and dysregulation of brain-gut interaction, but clinical tests for objectively defining gastric motor function are lacking. A medical device enabling noninvasive body surface gastric mapping (BSGM) was developed and applied to evaluate NVS pathophysiology. BSGM was performed in 43 patients with NVS and 43 matched controls using Gastric Alimetry (Alimetry), a conformable high-resolution array (8 × 8 electrodes; 20-mm interelectrode spacing), wearable reader, and validated symptom-logging app. Continuous measurement encompassed a fasting baseline (30 minutes), 482-kilocalorie meal, and 4-hour postprandial recording, followed by spectral and spatial biomarker analyses. Meal responses were impaired in NVS, with reduced amplitudes compared to controls (median, 23.3 microvolts versus 38.0 microvolts,

Indexed as

Gastric EmptyingNauseaHumansStomachSyndromeVomiting

Identifiers

PMID36130019
PMCPMC10042458
OpenAlexW4296706290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.