Evidence map›Paper›PMID 36129905›Full record

SynthesisPloS one2022

Socio-economic deprivation and cancer incidence in England: Quantifying the role of smoking.

Nick W S Payne, Katrina F Brown, Christine Delon, Yannis Kotrotsios, Isabelle Soerjomataram, Jon Shelton

Abstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Multiple Primary Cancer Incidence by County-Level Smoking Prevalence among U.S. Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nick W S PaynePolicy, Information and Communication Directorate, Cancer Research UK, London, United Kingdom.ORCID 0000-0003-0230-3948
Katrina F BrownPolicy, Information and Communication Directorate, Cancer Research UK, London, United Kingdom.
Christine DelonPolicy, Information and Communication Directorate, Cancer Research UK, London, United Kingdom.
Yannis KotrotsiosPolicy, Information and Communication Directorate, Cancer Research UK, London, United Kingdom.
Isabelle SoerjomataramSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
Jon SheltonPolicy, Information and Communication Directorate, Cancer Research UK, London, United Kingdom.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundMore deprived populations typically experience higher cancer incidence rates and smoking prevalence compared to less deprived populations. We calculated the proportion of cancer cases attributable to smoking by socio-economic deprivation in England and estimated the impact smoking has on the deprivation gap for cancer incidence.

methodsData for cancer incidence (2013-2017), smoking prevalence (2003-2007) and population estimates (2013-2017) were split by sex, age-group and deprivation quintile. Relative risk estimates from meta-analyses were used to estimate the population attributable fraction (PAF) for 15 cancer types associated with smoking. The deprivation gap was calculated using age-specific incidence rates by deprivation quintile.

resultsSmoking-related cancer PAFs in England are 2.2 times larger in the most deprived quintile compared to the least deprived quintile (from 9.7% to 21.1%). If everyone had the same smoking prevalence as the least deprived quintile, 20% of the deprivation gap in cancer incidence could have been prevented. If nobody smoked, 61% of the deprivation gap could have been prevented.

conclusionsThe majority of the deprivation gap in cancer incidence could have been prevented in England between 2013-2017 if nobody had smoked. Policy makers should ensure that tobacco control policies reduce overall smoking prevalence by tackling smoking inequalities.

Indexed as

NeoplasmsPovertyEnglandHumansIncidenceSmokingSocioeconomic Factors

Identifiers

PMID36129905
PMCPMC9491592

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.