ArticleIEEE transactions on bio-medical engineering2023
Lens Free Holographic Imaging for Urinary Tract Infection Screening.
Article in IEEE transactions on bio-medical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 0 citations in OpenAlex.
- Article
- Maskless and on-chip LED-array microscope with spatially-varying angle calibration for centimeter-scale phase imaging.bioRxiv : the preprint server for biology · 2025Article
- Optimised RFO tuned RF-DETR model for precision urine microscopy for renal and systemic disease diagnosis.Scientific reports · 2025Article
- Adaptive sparse reconstruction for lensless digital holography via PSF estimation and phase retrieval.Optics express · 2022Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe diagnosis of urinary tract infection (UTI) currently requires precise specimen collection, handling infectious human waste, controlled urine storage, and timely transportation to modern laboratory equipment for analysis. Here we investigate holographic lens free imaging (LFI) to show its promise for enabling automatic urine analysis at the patient bedside.
methodsWe introduce an LFI system capable of resolving important urine clinical biomarkers such as red blood cells, white blood cells, crystals, and casts in 2 mm thick urine phantoms.
resultsThis approach is sensitive to the particulate concentrations relevant for detecting several clinical urine abnormalities such as hematuria and pyuria, linearly correlating to ground truth hemacytometer measurements with R
conclusionLFI is sensitive to clinically-relevant concentrations of bacteria, blood cells, and other sediment in large urine volumes. SIGNIFICANCE: Together, these results show promise for LFI as a tool for urine screening, potentially offering early, point-of-care detection of UTI and other pathological processes.
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