Evidence map›Paper›PMID 36129775›Full record

ArticleMolecular biology of the cell2022

Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in

Ruizhen Li, Yanping Ren, Guolong Mo, Zackary Swider, Katsuhiko Mikoshiba, William M Bement, X Johné Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. In Vitro Models of Amyotrophic Lateral Sclerosis.Cellular and molecular neurobiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Ruizhen LiOttawa Hospital Research Institute, The Ottawa Hospital-General Campus, Ottawa, ON K1H 8L6, Canada.
Yanping RenOttawa Hospital Research Institute, The Ottawa Hospital-General Campus, Ottawa, ON K1H 8L6, Canada.
Guolong MoOttawa Hospital Research Institute, The Ottawa Hospital-General Campus, Ottawa, ON K1H 8L6, Canada.
Zackary SwiderGraduate Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI 53706.
Katsuhiko MikoshibaSIAIS ShanghaiTech University, Middle Huaxia Road, Shanghai 201210, China.
William M BementGraduate Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI 53706.
X Johné LiuOttawa Hospital Research Institute, The Ottawa Hospital-General Campus, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0003-3381-5030
University of Ottawa · CAUniversity of Wisconsin–Madison · USOttawa Hospital · CAToho University · JPZunyi Medical University · CN

Funding

Transient cytoskeletal arraysR01GM052932 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BEMENT, WILLIAM · 1997 to 2023
$7.2M
CIHR PJT-168891NIGMS NIH HHS R01 GM052932
6 · The paper itself

Abstract

The extent to which calcium signaling participates in specific events of animal cell meiosis or mitosis is a subject of enduring controversy. We have previously demonstrated that buffering intracellular calcium with 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA, a fast calcium chelator), but not ethylenebis(oxyethylenenitrilo)tetraacetic acid (EGTA, a slow calcium chelator), rapidly depolymerizes spindle microtubules in

Indexed as

CalciumInositolAnimalsCalcium Chelating AgentsMeiosisMicrotubulesOocytesSpindle ApparatusXenopus laevisCalciumCalcium Chelating AgentsInositol

Identifiers

PMID36129775
PMCPMC9727787
OpenAlexW4296703857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.