Evidence map›Paper›PMID 36129630›Full record

ArticleJournal of assisted reproduction and genetics2022

Lrriq1 is an essential factor for fertility by suppressing apoptosis.

Mayu Fukutomi, Chiharu Uedono, Aki Fujii, Youichi Sato

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mayu FukutomiDepartment of Pharmaceutical Information Science, Tokushima University Graduate School of Biomedical Sciences, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Chiharu UedonoDepartment of Pharmaceutical Information Science, Tokushima University Graduate School of Biomedical Sciences, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Aki FujiiDepartment of Pharmaceutical Information Science, Tokushima University Graduate School of Biomedical Sciences, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Youichi SatoDepartment of Pharmaceutical Information Science, Tokushima University Graduate School of Biomedical Sciences, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan. youichi.sato@tokushima-u.ac.jp.ORCID http://orcid.org/0000-0003-2224-552X
Tokushima University · JP

Funding

Grant-in-Aids for Scientific Research (B) 17H04331
6 · The paper itself

Abstract

purposeLeucine-rich repeats and IQ motif containing 1 (LRRIQ1) gene is reportedly associated with plasma inhibin B levels. However, the function of LRRIQ1 remains unknown. In this study, we generated Lrriq1 knockout mice (Lrriq1

methodsLrriq1

resultsExpression analysis of inhibin B revealed that Lrriq1

conclusionLrriq1 knockout reduced sperm motility and litter size by inducing apoptosis of testicular germ cells and epididymal sperm.

Indexed as

SemenSperm MotilityAnimalsApoptosisFertilityMaleMiceMice, KnockoutSpermatozoaSperm CountTestisApoptosisFertilityInhibin BLrriq1Sperm motility

Identifiers

PMID36129630
PMCPMC9723037
OpenAlexW4296962287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.