Evidence map›Paper›PMID 36129602›Full record

SynthesisSleep & breathing = Schlaf & Atmung2023

Impact of obstructive sleep apnea on cancer risk: a systematic review and meta-analysis.

Donghong Wu, Zifan Zhao, Changhui Chen, Guanjie Lu, Chuqiao Wang, Sirui Gao, Jieni Shen, Jun Liu, Jianxing He, Wenhua Liang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. [Research Advances in Obstructive Sleep Apnea and Lung Cancer Comorbidity].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026
    Review
  7. Article
  8. Sleep disorders in hepatocellular carcinoma.World journal of gastrointestinal oncology · 2025
    Review
  9. Cancer and obstructive sleep apnea.Chinese medical journal · 2025
    Article
  10. Relationship between sleep apnea and dizziness: a scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Impact of sleep on gastrointestinal cancer.World journal of clinical oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Donghong Wu *Department of Thoracic Oncology and Surgery, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510120, China.
Zifan Zhao *Nanshan School, Guangzhou Medical University, Guangzhou, China.
Changhui Chen *Nanshan School, Guangzhou Medical University, Guangzhou, China.
Guanjie Lu *Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, China.
Chuqiao WangDepartment of Thoracic Oncology and Surgery, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510120, China.
Sirui GaoNanshan School, Guangzhou Medical University, Guangzhou, China.
Jieni ShenNanshan School, Guangzhou Medical University, Guangzhou, China.
Jun LiuDepartment of Thoracic Oncology and Surgery, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510120, China.
Jianxing HeSouthern Medical University, Guangzhou, China. drjianxing.he@gmail.com.
Wenhua LiangDepartment of Thoracic Oncology and Surgery, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510120, China. liangwh1987@163.com.
Guangzhou Medical University · CNState Key Laboratory of Respiratory Disease · CNSouthern Medical University · CNThe First People's Hospital of Zhaoqing · CN

Funding

China National Science Foundation No. 81871893China National Science Foundation No. 82022048Key Project of Guangzhou Scientific Research Project No. 201804020030
6 · The paper itself

Abstract

purposeWe aimed to study the effect of obstructive sleep apnea (OSA) on cancer risk.

methodsWe searched PubMed, Embase, and Cochrane databases for relevant studies. The qualities of included studies were assessed using Newcastle-Ottawa Scale (NOS). Unadjusted and adjusted analyses were performed. We also conducted subgroup analyses stratified by gender, severity of OSA, study design, and cancer type.

resultsAfter literatures search, 18 studies were included in the present study. In the unadjusted analysis, we discovered an increased cancer risk in patients with OSA with a pooled relative risk (RR) in the OSA group of 1.49 (95% confidence interval (CI): 1.32-1.69, I

conclusionsThis systematic review and meta-analysis suggests that obstructive sleep apnea may increase risk of cancer.

Indexed as

Breast NeoplasmsSleep Apnea, ObstructiveCross-Sectional StudiesFemaleHumansProspective StudiesRetrospective StudiesRiskCancer riskMeta-analysisObstructive sleep apnea

Identifiers

PMID36129602
OpenAlexW4296962290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.