Evidence map›Paper›PMID 36129558›Full record

ReviewClinical and experimental medicine2023

Kidney function and renal resistive index in children with juvenile idiopathic arthritis.

Alessandro Cafarotti, Maria Loredana Marcovecchio, Giuseppe Lapergola, Caterina Di Battista, Manuela Marsili, Raffaella Basilico, Giulia Di Donato, Daniela David, Piernicola Pelliccia, Francesco Chiarelli and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Alessandro CafarottiDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Maria Loredana MarcovecchioDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
Giuseppe LapergolaDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Caterina Di BattistaDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Manuela MarsiliDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Raffaella BasilicoDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", Chieti, Italy.
Giulia Di DonatoDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Daniela DavidDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Piernicola PellicciaDepartment of Paediatrics, Renzetti Hospital, Lanciano, Italy.
Francesco ChiarelliDepartment of Paediatrics, University "G. d'Annunzio", Chieti, Italy.
Luciana BredaPediatric Rheumatology Unit, S.S. Annunziata Hospital, Via dei Vestini 5, Chieti, Italy. luciana.bredach@gmail.com.
University of Chieti-Pescara · ITOspedale "Floraspe Renzetti" · ITOspedale SS. Annunziata · ITUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile idiopathic arthritis (JIA) is a common pediatric rheumatic disease. Renal manifestations have been rarely observed in JIA, although amyloidosis could be a renal complication in systemic JIA (sJIA). To investigate renal damage in JIA children and to establish the relationship with treatment. Blood urea nitrogen (BUN), creatinine, cystatin C (CysC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), urinary albumin excretion (UAE), estimated glomerular filtration rate (eGFR), and renal resistive index (RRI) were assessed in 49 JIA children (9 boys/40 girls, mean age 10.3 ± 3.8 years) and in 49 healthy controls (24 boys/25 girls, mean age 11.3 ± 3.4 years). Twenty-two JIA patients were on methotrexate (MTX) therapy (group A) and 27 on biologic drugs (group B). CysC and BUN (respectively, 0.8 ± 0.1 vs. 0.7 ± 0.1 mg/dl; 13.3 ± 2.9 vs. 11.7 ± 1.4 mg/dl) were higher (p ≤ 0.001) whereas creatinine and eGFR (respectively, 0.5 ± 0.1 vs. 0.6 ± 0.1 mg/dl; 99.2 ± 10.5 vs. 122.5 ± 19.8 ml/min/1.73 m

Indexed as

Arthritis, JuvenileAdolescentChildCreatinineFemaleHumansInflammationKidneyMaleMethotrexateCreatinineMethotrexateCystatin CJuvenile arthritisKidneyRenal damageRenal resistive indexUrinary albumin excretion

Identifiers

PMID36129558
PMCPMC10284920
OpenAlexW4296966021

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.