Evidence map›Paper›PMID 36129526›Full record

ArticleAnalytical and bioanalytical chemistry2022

Real-time monitoring of 5-HT release from cells based on MXene hybrid single-walled carbon nanotubes modified electrode.

Mengyuan Jiang, Liang Tian, Mengjie Su, Xiaoqing Cao, Qiyu Jiang, Xiaolei Huo, Chunmei Yu

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Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengyuan JiangSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Liang TianSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Mengjie SuSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Xiaoqing CaoSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Qiyu JiangSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Xiaolei HuoSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China.
Chunmei YuSchool of Public Health, Nantong University, Nantong, 226019, People's Republic of China. cmyu@ntu.edu.cn.

Funding

National Natural Science Foundation of China 82173570
6 · The paper itself

Abstract

Serotonin (5-HT) is an essential inhibitory neurotransmitter in vivo that is critical for interneuronal communication of the nervous system. Herein, we constructed an electrochemical cell-sensing platform for 5-HT detection based on MXene/single-walled carbon nanotubes (SWCNTs) nanocomposite. The one-dimensional SWCNTs with good electrical conductivity are uniformly dispersed on the surface and intermediate layers of the two-dimensional MXene to form a tightly heterogeneous heterostructure. The synthesized MXene-SWCNTs could improve the stacking problem of MXene nanosheets and expose more active sites, effectively promoting the conductive properties and electrochemical activity of the composite. The fabricated MXene-SWCNTs/GCE possessed outstanding detection capability for 5-HT with a wide linear range of 4 nM-103.2 μM and a low detection limit of 1.5 nM. Moreover, the sensor was further applied for the real-time monitoring trace amount of 5-HT releasing from different cell lines, which confirmed its promising applications in 5-HT related physiological and pathological fields. MXene-SWCNTs/GCE was developed and applied for the real-time monitoring of trace amounts of 5-HT secreted from living cells.

Indexed as

Nanotubes, CarbonElectrochemical TechniquesElectrodesLimit of DetectionSerotoninNanotubes, CarbonSerotoninCell releaseElectrochemical sensorMXeneSerotoninSingle-walled carbon nanotube

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.