Evidence map›Paper›PMID 36129196›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2023

Prenatal exposure to a natural disaster and early development of psychiatric disorders during the preschool years: stress in pregnancy study.

Yoko Nomura, Jeffrey H Newcorn, Christine Ginalis, Catherine Heitz, Jeenia Zaki, Farzana Khan, Mardia Nasrin, Kathryn Sie, Donato DeIngeniis, Yasmin L Hurd

Open access · greenAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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  7. Behavioral moderators ofFrontiers in psychiatry · 2025
    Article
  8. Review
  9. Uncertainty in Developmental Origins of Health and Disease research: commentary on Nomura et al. (2023).Journal of child psychology and psychiatry, and allied disciplines · 2023
    Article
  10. The Impact of COVID-19 Related Distress on Antenatal Depression in Australia.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yoko Nomura *Department of Psychology, CUNY Queens College, Flushing, NY, USA.ORCID 0000-0002-2143-3257
Jeffrey H Newcorn *Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Christine GinalisDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Catherine HeitzDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Jeenia ZakiDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Farzana KhanDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Mardia NasrinDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Kathryn SieDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Donato DeIngeniisDepartment of Psychology, CUNY Queens College, Flushing, NY, USA.
Yasmin L HurdIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Queens College, CUNY · USIcahn School of Medicine at Mount Sinai · US

Funding

The Infants of Superstorm Sandy:The Epigenetic and Developmental Impact of Natural DisasterR01MH102729 · NIMH · QUEENS COLLEGE · PI NOMURA, YOKO · 2014 to 2018
$3.5M
NIMH NIH HHS R01 MH102729
6 · The paper itself

Abstract

backgroundGrowing evidence shows an association between in utero exposure to natural disasters and child behavioral problems, but we still know little about the development of specific psychopathology in preschool-aged children.

methodsPreschool children (n = 163, mean age = 3.19, 85.5% racial and ethnic minorities) and their parents (n = 151) were evaluated annually at ages 2-5 to assess the emergence of psychopathology using the Preschool Age Psychopathological Assessment (PAPA), a parent-report structured diagnostic interview developed for preschool-age children. Sixty-six (40.5%) children were exposed to Sandy Storm (SS) in utero and 97 (59.5%) were not. Survival analysis evaluated patterns of onset and estimated cumulative risks of psychopathology among exposed and unexposed children, in total and by sex. Analyses were controlled for the severity of objective and subjective SS-related stress, concurrent family stress, and demographic and psychosocial confounders, such as maternal age, race, SES, maternal substance use, and normative prenatal stress.

resultsExposure to SS in utero was associated with a substantial increase in depressive disorders (Hazard Ratio (HR) = 16.9, p = .030), anxiety disorders (HR = 5.1, p < .0001), and attention-deficit/disruptive behavioral disorders (HR = 3.4, p = .02). Diagnostic rates were elevated for generalized anxiety disorder (GAD; HR = 8.5, p = .004), attention-deficit/hyperactivity disorder (ADHD; HR = 5.5, p = .01), oppositional-defiant disorder (ODD; HR = 3.8, p = .05), and separation-anxiety disorder (SAD; HR = 3.5, p = .001). Males had distinctively elevated risks for attention-deficit/disruptive behavioral disorders (HR = 7.8, p = .02), including ADHD, CD, and ODD, whereas females had elevated risks for anxiety disorders (HR = 10.0, p < .0001), phobia (HR = 2.8, p = .02) and depressive disorders (HR = 30.0, p = .03), including SAD, GAD, and dysthymia.

conclusionsThe findings demonstrate that in utero exposure to a major weather-related disaster (SS) was associated with increased risk for psychopathology in children and provided evidence of distinct psychopathological outcomes as a function of sex. More attention is needed to understand specific parent, child, and environmental factors which account for this increased risk, and to develop mitigation strategies.

Indexed as

Attention Deficit Disorder with HyperactivityNatural DisastersPrenatal Exposure Delayed EffectsAttention Deficit and Disruptive Behavior DisordersChild, PreschoolComorbidityFemaleHumansMalePregnancyanxietydevelopmental psychopathologydisruptive behaviorNatural disasterssex differences

Identifiers

PMID36129196
PMCPMC10027622
OpenAlexW4296704798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.