Evidence map›Paper›PMID 36129180›Full record

ArticleeLife2022

Higher-order unimodal olfactory sensory preconditioning in

Juan Martinez-Cervantes, Prachi Shah, Anna Phan, Isaac Cervantes-Sandoval

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Cognitive limits of larvalLearning & memory (Cold Spring Harbor, N.Y.) · 2024
    Article
  7. Diverse memory paradigms inLearning & memory (Cold Spring Harbor, N.Y.) · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Juan Martinez-Cervantes *Department of Biology, Georgetown University, Washington, DC, United States.
Prachi Shah *Department of Biology, Georgetown University, Washington, DC, United States.
Anna PhanDepartment of Biological Sciences and Neuroscience & Mental Health Institute, University of Alberta, Edmonton, Canada.
Isaac Cervantes-SandovalDepartment of Biology, Georgetown University, Washington, DC, United States.ORCID 0000-0002-6372-7288
Georgetown University · USWomen and Children’s Health Research Institute · CA

Funding

Aging and Alzheimer's Research Training (AART)T32AG071745 · NIA · GEORGETOWN UNIVERSITY · PI G WILLIAM REBECK · 2021 to 2026
$2.6M
Scribble signalosome and active forgettingR21MH117485 · NIMH · SCRIPPS FLORIDA · PI CERVANTES SANDOVAL, ISAAC · 2019 to 2020
$427k
NIA NIH HHS T32 AG071745NIMH NIH HHS R21 MH117485
6 · The paper itself

Abstract

Learning and memory storage is a complex process that has proven challenging to tackle. It is likely that, in nature, the instructive value of reinforcing experiences is acquired rather than innate. The association between seemingly neutral stimuli increases the gamut of possibilities to create meaningful associations and the predictive power of moment-by-moment experiences. Here, we report physiological and behavioral evidence of olfactory unimodal sensory preconditioning in fruit flies. We show that the presentation of a pair of odors (S1 and S2) before one of them (S1) is associated with electric shocks elicits a conditional response not only to the trained odor (S1) but to the odor previously paired with it (S2). This occurs even if the S2 odor was never presented in contiguity with the aversive stimulus. In addition, we show that inhibition of the small G protein

Indexed as

DrosophilaMonomeric GTP-Binding ProteinsAnimalsConditioning, ClassicalDrosophila melanogasterOdorantsSmellMonomeric GTP-Binding Proteinsclassical conditioningD. melanogasterDrosophilaforgettinghigh-order conditioninglearningmemoryneurosciencesensory preconditioning

Identifiers

PMID36129180
PMCPMC9566850
OpenAlexW4297874868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.