Evidence map›Paper›PMID 36129050›Full record

ArticleJournal of the American Heart Association2022

Feasibility of Quantitative Flow Ratio Virtual Stenting for Guidance of Serial Coronary Lesions Intervention.

Shaofeng Guan, Qian Gan, Wenzheng Han, Xinrong Zhai, Ming Wang, Yang Chen, Liang Zhang, Tianqi Li, Xifeng Chang, Hongyuan Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Functional or anatomical assessment of non-culprit lesions in acute myocardial infarction.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  4. Accuracy of coronary computed tomography angiography-derived quantitative flow ratio for onsite assessment of coronary lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Shaofeng GuanDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Qian GanDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.ORCID 0000-0002-0153-3816
Wenzheng HanDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Xinrong ZhaiDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Ming WangDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Yang ChenDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Liang ZhangDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Tianqi LiDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Xifeng ChangDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Hongyuan LiuDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Weilin HongDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.
Zehang LiShanghai Jiao Tong University-Pulse Medical Imaging Joint Laboratory Shanghai China.ORCID 0000-0002-4264-8409
Shengxian TuBiomedical Instrument Institute, School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China.ORCID 0000-0001-9681-1067
Xinkai QuDepartment of Cardiology Huadong Hospital Affiliated to Fudan University Shanghai China.ORCID 0000-0002-5000-6721
Fudan University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Coronary physiology measurement in serial coronary lesions with multiple stenoses is challenging. Therefore, we evaluated the feasibility of Murray fractal law-based quantitative flow ratio (μQFR) virtual stenting for guidance of serial coronary lesions intervention. Methods and Results Patients who underwent elective coronary angiography and had 2 serial de novo coronary lesions of 30% to 90% diameter stenosis by visual estimation were prospectively enrolled. μQFR and fractional flow reserve (FFR) were assessed after coronary angiography. In vessels with an FFR ≤0.80, the lesion with the larger pressure gradient was considered to be the primary lesion and treated firstly, followed by FFR measurement. The second lesion was stented when FFR ≤0.80. All μQFR and predicted μQFR after stenting were calculated from diagnostic coronary angiography before interventions, with the analysts masked to the FFR data. A total of 54 patients with 61 target vessels were interrogated. Percutaneous coronary intervention was performed in 44 vessels with FFR ≤0.80. After stenting the primary lesions, 14 nonprimary lesions had FFR ≤0.80 and a second drug-eluting stent was implanted. There was excellent correlation (

Indexed as

Coronary Artery DiseaseCoronary StenosisDrug-Eluting StentsFractional Flow Reserve, MyocardialPercutaneous Coronary InterventionCoronary AngiographyCoronary VesselsFeasibility StudiesHumansStentsquantitative flow ratioserial coronary lesionsvirtual stenting

Identifiers

PMID36129050
PMCPMC9673740
OpenAlexW4296710286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.