Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
33 authors at 8 institutions in 2 countries.
Flemming Javier OlsenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0001-9511-8375
Mats Christian Højbjerg LassenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-2255-582X
Kristoffer Grundtvig SkaarupDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-2690-7511
Jacob ChristensenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-4231-0299
Filip Soeskov DavidovskiDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-6642-416X
Alia Saed AlhakakDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.
Morten SengeløvDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.
Anne Bjerg NielsenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-0624-5936
Niklas Dyrby JohansenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0001-6959-3236
Claus GraffDepartment of Health Science and Technology Aalborg University Aalborg Denmark.
Henning BundgaardDepartment of Cardiology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-0563-7049
Christian HassagerDepartment of Cardiology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-1199-0981
Reza JabbariDepartment of Cardiology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Jørn CarlsenDepartment of Cardiology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.ORCID 0000-0003-0389-5957
Ole KirkDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.
Matias Greve LindholmDepartment of Cardiology Zealand University Hospital Roskilde Denmark.
Lothar WieseDepartment of Infectious Diseases Zealand University Hospital Roskilde Denmark.
Ole Peter KristiansenDepartment of Cardiology Copenhagen University Hospital - Bispebjerg and Frederiksberg Copenhagen Denmark.
Olav W NielsenDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.ORCID 0000-0003-3532-9431
Birgitte LindegaardDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.
Niels TønderDepartment of Cardiology Copenhagen University Hospital - North Zealand Hilleroed Denmark.
Charlotte Suppli UlrikDepartment of Respiratory Medicine Copenhagen University Hospital - Amager and Hvidovre Hvidovre Denmark.ORCID 0000-0001-8689-3695
Morten LambertsDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-9827-440X
Pradeesh SivapalanDepartment of Medicine Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.
Gunnar GislasonDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-0548-402X
Kasper IversenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0003-0504-8487
Jens Ulrik Stæhr JensenDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.ORCID 0000-0003-4036-0521
Morten SchouDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0002-4271-2466
Jesper Hastrup SvendsenDepartment of Cardiology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.ORCID 0000-0001-8466-8515
John Moene AalenInstitute for Surgical Research, Rikshospitalet Oslo University Hospital and University of Oslo Oslo Norway.
Otto Armin SmisethInstitute for Surgical Research, Rikshospitalet Oslo University Hospital and University of Oslo Oslo Norway.
Espen Wattenberg RemmeInstitute for Surgical Research, Rikshospitalet Oslo University Hospital and University of Oslo Oslo Norway.
Tor Biering-SørensenDepartment of Cardiology Copenhagen University Hospital - Herlev and Gentofte Hellerup Denmark.ORCID 0000-0003-4209-2778
University of Copenhagen · DKGentofte Hospital · DKCopenhagen University Hospital · DKOslo University Hospital · NOZealand University Hospital · DKAalborg University · DKFrederiksberg Hospital · DKHvidovre Hospital · DK
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Background COVID-19 infection has been hypothesized to affect left ventricular function; however, the underlying mechanisms and the association to clinical outcome are not understood. The global work index (GWI) is a novel echocardiographic measure of systolic function that may offer insights on cardiac dysfunction in COVID-19. We hypothesized that GWI was associated with disease severity and all-cause death in patients with COVID-19. Methods and Results In a multicenter study of patients admitted with COVID-19 (n=305), 249 underwent pressure-strain loop analyses to quantify GWI at a median time of 4 days after admission. We examined the association of GWI to cardiac biomarkers (troponin and NT-proBNP [N-terminal pro-B-type natriuretic peptide]), disease severity (oxygen requirement and CRP [C-reactive protein]), and all-cause death. Patients with elevated troponin (n=71) exhibited significantly reduced GWI (1508 versus 1707 mm Hg%;
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Myocardial Work in Patients Hospitalized With COVID-19: Relation to Biomarkers, COVID-19 Severity, and All-Cause Mortality. · full record | OpenQuestion