Evidence map›Paper›PMID 36128868›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Novel 2-phenyl-4H-chromen derivatives: synthesis and anti-inflammatory activity evaluation

Yun Xiao, Yaoyao Yan, Juncheng Du, Xiaoxiao Feng, Famin Zhang, Xu Han, Yong Hu, Xinhua Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yun XiaoSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Yaoyao YanSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Juncheng DuSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Xiaoxiao FengSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Famin ZhangSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Xu HanSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Yong HuAnhui Academy of Agricultural Sciences, Agricultural Products Processing Institute, Hefei, P. R. China.
Xinhua LiuSchool of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, P. R. China.
Anhui Medical University · CNAnhui Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is significant to design, synthesise and optimise flavonoid derivatives with better anti-inflammatory activity. This study aims to design and synthesise a series of novel 2-phenyl-4H-chromen-4-one compounds with anti-inflammatory; among them, compound

Indexed as

LipopolysaccharidesTumor Necrosis Factor-alphaAnimalsAnti-Inflammatory AgentsFlavonoidsInflammationInterleukin-6MiceToll-Like Receptor 4Anti-Inflammatory AgentsFlavonoidsInterleukin-6LipopolysaccharidesToll-Like Receptor 4Tumor Necrosis Factor-alpha2-Phenyl-4H-chromen-4-one derivativesanti-inflammatoryTLR4/MAPK pathway

Identifiers

PMID36128868
PMCPMC9518258
OpenAlexW4296703184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.