ArticleJournal of pathology and translational medicine2022
Evaluation of the characteristics of multiple human papillomavirus (HPV) infections identified using the BD Onclarity HPV assay and comparison with those of single HPV infection.
Article in Journal of pathology and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 14 citations in OpenAlex.
- An epidemiological survey of HPV infection among women in Southern Hebei, China.Virology journal · 2026Article
- The association of pathological findings in HPV-31 positive women with high-grade squamous intraepithelial lesions.Journal of the Turkish German Gynecological Association · 2026Article
- Dynamic changes of HPV genotypes in a tourism-influenced populated area, Northeastern Iran.PloS one · 2026Article
- Informative HPV testing after conization and its impact on time-varying estimates: a GAMM-based cohort study.Frontiers in public health · 2026Article
- Multiple high-risk human papillomavirus infections exacerbate cervical lesion risk: epidemiological evidence from suining, Sichuan.Virology journal · 2025Article
- The Prevalence of Multi-Type Infections Among Human Papillomavirus Types in Korean Women.Pathogens (Basel, Switzerland) · 2025Article
- Nanopore sequencing of non-oncogenic oral Papillomaviruses from people living with HIV.Research square · 2025Article
- Molecular findings and virological assessment of bladder papillomavirus infection in cattle.The veterinary quarterly · 2024Article
- Patterns of single and multiple HPV infections in female: A systematic review and meta-analysis.Heliyon · 2024Article
- The cervical cancer related distribution, coinfection and risk of 15 HPV types in Baoan, Shenzhen, in 2017-2023.Virology journal · 2024Article
- Epidemiologic characteristics of high-risk HPV and the correlation between multiple infections and cervical lesions.BMC infectious diseases · 2023Article
- Relative distribution of HPV genotypes in histological cervical samples and associated grade lesion in a women population over the last 16 years in Burgundy, France.Frontiers in medicine · 2023Article
- Gastric-type Endocervical Adenocarcinoma: Comprehensive Cytopathological Analysis and Comparison With Usual-type Endocervical Adenocarcinoma.In vivo (Athens, Greece)Review
- Prevalence of Multiple High Risk Human Papilloma Virus (HR-HPV) Infections in Cervical Cancer Screening in Lazio Region, Italy.Cancer diagnosis & prognosisArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHuman papillomavirus (HPV) infection is a major cause of cervical cancer and associated precursor lesions. Multiple HPV genotype infections have been reported. However, their clinicopathological characteristics still remain elusive.
methodsFor this study, 814 consecutive patients who had undergone colposcopy and HPV genotyping test using BD Onclarity HPV assay were retrospectively selected. Clinicopathological parameters of multiple HPV infections were compared with those of single HPV infection.
resultsMultiple HPV infections were found in 110 out of 814 cases (13.5%). Multiple HPV infections were associated with a significantly higher incidence of high-grade intraepithelial lesions (HSILs) compared with single HPV infection. Other high-risk HPV genotypes, in addition to HPV 16, were found more frequently in the multiple HPV infections group; these included HPV 51, 52, 33/58, 56/59/66, and 35/39/68. No specific coinfection pattern was not identified. Additionally, the number of HPV genotypes in multiple HPV infections was not associated with the progression to HSIL or squamous cell carcinoma.
conclusionsMultiple HPV infections have distinct clinicopathological characteristics (compared with single HPV infection). As their biological behavior is uncertain, close and frequent follow-up is warranted.
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