Evidence map›Paper›PMID 36128719›Full record

ArticleOpen biology2022

Molecular characteristics of the edge cells responsible for expansion of the chick embryo on the vitelline membrane.

Hyung Chul Lee, Yara Fadaili, Claudio D Stern

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Molecular basis of competence for neural induction in the chick embryo.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hyung Chul LeeDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.ORCID 0000-0001-5438-1900
Yara FadailiDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.
Claudio D SternDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.ORCID 0000-0002-9907-889X
University College London · GB

Funding

Wellcome Trust 107055/Z/15/Z
6 · The paper itself

Abstract

During early avian development, only a narrow band of cells (the edge cells, also called 'margin of overgrowth') at the rim of the embryo is responsible for blastoderm expansion by crawling over the vitelline membrane (VM) to cover the whole egg yolk in just 4 days (a process called epiboly). Surprisingly, this has not yet been studied in detail. Here we explore the edge cells of the chick embryo using

Indexed as

BlastodermVitelline MembraneAnimalsCell MovementChick EmbryoEpithelial CellsWound Healingcell polarityepithelial–mesenchymal transition (EMT)epithelial sheet fusionmesenchyme–epithelial transition (MET)

Identifiers

PMID36128719
PMCPMC9490332
OpenAlexW4296702995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.