Evidence map›Paper›PMID 36128646›Full record

ArticleJournal of cellular and molecular medicine2022

tRNA-derived fragment tRF-1020 ameliorates diabetes-induced retinal microvascular complications.

Cong Ma, Jianling Du, Xiang Ma

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Transfer RNA Fragments in Diseases of Sensory Organs.International journal of molecular sciences · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. A Novel tRNA-Derived Fragment, tRFInternational journal of molecular sciences · 2023
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cong MaDepartment of Ophthalmology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Jianling DuDepartment of the Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.ORCID 0000-0001-9042-6969
Xiang MaDepartment of Ophthalmology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Dalian Medical University · CN

Funding

National Natural Science Foundation of China 81570727
6 · The paper itself

Abstract

Transfer RNA (tRNA)-derived fragments are the non-coding single-stranded RNAs involved in several physiological and pathological processes. Herein, we investigated the role of tRF-1020, a tRNA fragment, in diabetes-induced retinal microvascular complications. The results showed that the levels of tRF-1020 expression were down-regulated in diabetic retinal vessels and retinal endothelial cells following high glucose or H

Indexed as

Diabetes MellitusDiabetic RetinopathyEndothelial CellsGlucoseHumansRetinaRNA, TransferGlucoseRNA, Transferangiogenic functionretinal microvascular complicationtRNA-derived RNA fragmentWnt signalling

Identifiers

PMID36128646
PMCPMC9575064
OpenAlexW4297874892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.