Evidence map›Paper›PMID 36128077›Full record

ArticleJournal of current glaucoma practice

Pattern Electroretinogram Parameters and their Associations with Optical Coherence Tomography in Glaucoma Suspects.

Andrew Tirsi, Amanda Wong, Daniel Zhu, Guillaume Stoffels, Peter Derr, Celso Tello Md

Open access · diamondAbstract read
In one paragraph

Article in Journal of current glaucoma practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Andrew TirsiDepartment of Ophthalmology, Manhattan Eye, Ear, & Throat Hospital, Northwell Health, New York, United States; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.ORCID https://orcid.org/0000-0002-8424-7574
Amanda WongDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.
Daniel ZhuDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.ORCID https://orcid.org/0000-0001-6569-9623
Guillaume StoffelsLennox Hill Hospital/Northwell, Feinstein Institute for Medical Research, New York, United States.
Peter DerrDiopsys, Inc., Pine Brook, NJ, United States.
Celso Tello MdDepartment of Ophthalmology, Manhattan Eye, Ear, & Throat Hospital, Northwell Health, New York, United States; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, United States.
Northwell Health · USDonald & Barbara Zucker School of Medicine at Hofstra/Northwell · USFeinstein Institute for Medical Research · USManhattan Eye, Ear and Throat Hospital · USSynopsys (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate whether steady state pattern electroretinogram (ssPERG) could identify retinal ganglion cell (RGC) dysfunction, and to assess the relationship between ssPERG with optical coherence tomography (OCT) measurements in glaucoma suspects (GS). Materials and methods: This was a prospective cohort study of GS, identified based on suspicious optic disk appearance and glaucoma risk factors. Complete eye exam, Standard automated perimetry, OCT, and ssPERG were performed. Magnitude (Mag), Magnitude D (MagD), and MagD/Mag ratio were subsequently used in the correlation and linear regression analyses between ssPERG parameters and the RNFL, GCL/IPL, and macular thicknesses measurements. Results: Forty-nine eyes of 26 patients were included. Mag and MagD were significantly correlated with the superior, inferior, and average RNFL thicknesses (avRNFLT). All ssPERG parameters were significantly correlated with the average and minimum GCL/IPL thicknesses and the inner macular sector thicknesses. Mag and MagD significantly predicted the superior, inferior, and avRNFLT in the regression analysis. All ssPERG parameters were predictive of GCL/IPL thickness in all sectors as well as the average and minimum GCL/IPL thicknesses. All ssPERG parameters were predictive of all inner macular sector thicknesses and MagD was also predictive of some outer macular sector thicknesses as well. Conclusion: ssPERG has significant correlations with and is predictive of RNFL, GCL/IPL, and macular thicknesses in glaucoma suspects. Clinical significance: ssPERG may serve as a useful objective functional tool for identifying and following the progression of disease in glaucoma suspects. How to cite this article: Tirsi A, Wong A, Zhu D,

Indexed as

Ganglion cell layerGlaucomaGlaucoma suspectInner plexiform layerMaculaOptical coherence tomographyOptic nerveRetinal ganglion cellRetinal nerve fiber layerSteady state pattern electroretinogram

Identifiers

PMID36128077
PMCPMC9452702
OpenAlexW4293548513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.