Evidence map›Paper›PMID 36128070›Full record

ArticleJournal of medical cases2022

Anti-MDA5 Associated Clinically Amyopathic Dermatomyositis With Rapidly Progressive Interstitial Lung Disease.

Kameron Tavakolian, Mihir Odak, Anton Mararenko, Justin Ilagan, Steven Douedi, Taimoor Khan, Ghadier Al Saoudi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kameron TavakolianDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Mihir OdakDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Anton MararenkoDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Justin IlaganDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Steven DouediDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Taimoor KhanDepartment of Pulmonary and Critical Care, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Ghadier Al SaoudiDepartment of Pulmonary and Critical Care, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Jersey Shore University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-melanoma differentiation-associated protein 5 (anti-MDA5) associated clinically amyopathic dermatomyositis (CADM) is a rare entity that is frequently associated with rapidly progressive interstitial lung disease. The disease is characterized by its association with a distinct myositis specific antibody, the lack of muscle involvement seen with other inflammatory myopathies, and a strong correlation with the development of rapidly progressive interstitial lung disease. Diagnosis is based on clinical findings and the presence of autoantibodies. Management generally involves combination immunosuppression therapy. However, the disease course is often aggressive and lends a poor prognosis. We report a case of a healthy 55-year-old male who presented with dyspnea, dry cough, and joint pain for 1 month. The patient was diagnosed with anti-MDA5 associated CADM with interstitial lung disease after a complete rheumatological workup found elevated titers of MDA5 antibodies and computed tomography of the chest without contrast revealed radiographic evidence of interstitial lung involvement. Disease course was complicated by the development of

Indexed as

Anti-MDA antibodyClinically amyopathic dermatomyositisDyspneaHypoxiaIdiopathic inflammatory myositisMyositis specific antibodyRapidly progressive interstitial lung disease

Identifiers

PMID36128070
PMCPMC9451563
OpenAlexW4292315400

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.