Evidence map›Paper›PMID 36127938›Full record

ReviewPrzeglad gastroenterologiczny2022

Vonoprazan in the management of erosive oesophagitis and peptic ulcer-induced medication: a systematic review.

Décio Chinzon, Joaquim Prado P Moraes-Filho, Gerson Domingues, Juliana Leite Soares Guedes, Cláudia Yang Santos, Schlioma Zaterka

Open access · goldAbstract readReview
In one paragraph

Review in Przeglad gastroenterologiczny, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Acid peptic disorder compass: An Indian expert consensus on comprehensive management.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Décio ChinzonDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo, Brazil.
Joaquim Prado P Moraes-FilhoDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo, Brazil.
Gerson DominguesDepartment of Gastroenterology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Juliana Leite Soares GuedesTakeda Pharmaceuticals Brazil.
Cláudia Yang SantosTakeda Pharmaceuticals Brazil.
Schlioma ZaterkaDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo, Brazil.
Universidade de São Paulo · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Vonoprazan has been found to promote a better antisecretory effect addressing acid-related diseases' unmet needs. Aim: To assess if vonoprazan effectively treats patients diagnosed with gastroesophageal reflux disease esophagitis or with peptic ulcers induced by chronic use of aspirin or non-steroidal anti-inflammatory drugs. Material and methods: A literature search was conducted (April/2021) using Medline via PubMed, Cochrane library, Lilacs, Scielo, and Centre for Reviews and Dissemination electronic databases. Results: We retrieved 55 titles. Of these, 13 met the eligibility criteria and were included in this review. Of these 13 articles, 4 were prospective cohort studies, 1 was a follow-up analysis of a preceding prospective study, 1 was a retrospective cohort study, and 6 were randomized clinical trials. Conclusions: Our findings suggest that vonoprazan was effective and non-inferior to proton pump inhibitors in healing and maintaining healed reflux oesophagitis, leading to faster symptom relief. Vonoprazan may also be considered for preventing aspirin- or non-steroidal anti-inflammatory drug-related peptic ulcer recurrence.

Indexed as

gastroesophageal reflux diseaseoesophagitisproton pump inhibitorssystematic reviewulcer

Identifiers

PMID36127938
PMCPMC9475477
OpenAlexW4205488230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.