ReviewJournal of biomedical science2022
Pathophysiology of reversible cerebral vasoconstriction syndrome.
Review in Journal of biomedical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Idiopathic extracranial internal carotid artery vasospasm: case report and systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis.Journal of neurology · 2023Pooled it
- Reversible Cerebral Vasoconstriction Syndrome Associated With Vortioxetine: A Case Report.Cureus · 2026Article
- A delayed endothelial-glial mechanism for CGRP-induced migraine.The journal of headache and pain · 2026Review
- [Reversible Cerebral Vasoconstriction Syndrome Associated with Ileostomy and Blood Transfusion in a Patient with Advanced Gastric Cancer: A Case Report and Review of the Literature].Journal of the Korean Society of Radiology · 2026Article
- Blood-brain barrier integrity and brain entropy in reversible cerebral vasoconstriction syndrome.The journal of headache and pain · 2026Article
- Posterior reversible encephalopathy syndrome in drug-induced syndrome of inappropriate ADH secretion: a case report.Journal of medical case reports · 2026Article
- Review
- A Population-Based Study of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome During Pregnancy and Puerperium.European journal of neurology · 2026Article
- Article
- Reversible Cerebral Vasoconstriction Syndrome With Ischemic Stroke Underlying Ring Finger Protein 213 Vasculopathy.Journal of clinical neurology (Seoul, Korea) · 2026Article
- Blood Pressure Management in Neurologic Emergencies.Emergency medicine clinics of North America · 2026Review
- Systemic Arterial Stiffness in Reversible Cerebral Vasoconstriction Syndrome: A Prospective Case-Control Study.European journal of neurology · 2026Observational
- Article
- Catecholamine-Induced Reversible Cerebral Vasoconstriction Syndrome: An Overlooked Cause of Thunderclap Headache.Cureus · 2025Article
- Article
- Electrocoagulation therapy for a patient with an acute thalamoperforating artery pseudoaneurysm: a case report.BMC cardiovascular disorders · 2025Article
- Perfusion dynamics in reversible cerebral vasoconstriction syndrome.The journal of headache and pain · 2025Article
- Heterogeneous and lateralized cervical vascular responses to a 7-day head-down tilt bed rest.NPJ microgravity · 2025Article
- Concurrent Extracerebral Vasoconstriction in Patients with Reversible Cerebral Vasoconstriction Syndrome: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Reversible cerebral vasoconstriction syndrome (RCVS) is a complex neurovascular disorder being recognized during the past two decades. It is characterized by multiple abrupt severe headaches and widespread cerebral vasoconstrictions, with potential complications such as ischemic stroke, convexity subarachnoid hemorrhage, intracerebral hemorrhage and posterior reversible encephalopathy syndrome. The clinical features, imaging findings, and dynamic disease course have been delineated. However, the pathophysiology of RCVS remains elusive. Recent studies have had substantial progress in elucidating its pathogenesis. It is now believed that dysfunction of cerebral vascular tone and impairment of blood-brain barrier may play key roles in the pathophysiology of RCVS, which explains some of the clinical and radiological manifestations of RCVS. Some other potentially important elements include genetic predisposition, sympathetic overactivity, endothelial dysfunction, and oxidative stress, although the detailed molecular mechanisms are yet to be identified. In this review, we will summarize what have been revealed in the literature and elaborate how these factors could contribute to the pathophysiology of RCVS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.