Evidence map›Paper›PMID 36127692›Full record

ArticleAIDS research and therapy2022

Self-transfers and factors associated with successful tracing among persons lost to follow-up from HIV care, Sheema District, Southwestern Uganda: retrospective medical records review, 2017-2021.

Arnold Ssemwogerere, Javilla Kakooza Kamya, Lillian Nuwasasira, Claire Ahura, Derrick Isaac Isooba, Edith K Wakida, Celestino Obua, Richard Migisha

Abstract read
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Article in AIDS research and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Arnold SsemwogerereDepartment of Pharmacy, Mbarara University of Science and Technology, Mbarara, Uganda.
Javilla Kakooza KamyaDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Lillian NuwasasiraDepartment of Pharmaceutical Sciences, Mbarara University of Science and Technology, Mbarara, Uganda.
Claire AhuraDepartment of Nursing, Mbarara University of Science and Technology, Mbarara, Uganda.
Derrick Isaac IsoobaDepartment of Medical Laboratory Sciences, Mbarara University of Science and Technology, Mbarara, Uganda.
Edith K WakidaDepartment of Medical Education, California University of Science and Medicine, San Bernardino, USA.
Celestino ObuaOffice of Research Administration, Mbarara University of Science and Technology, Mbarara, Uganda.
Richard MigishaDepartment of Physiology, Mbarara University of Science and Technology, P.O BOX 1410, Mbarara, Uganda. rmigisha@must.ac.ug.

Funding

Health-professional Education Partnership Initiative - Transforming Ugandan Institutions Training Against HIV/AIDS (HEPI-TUITAH)R25TW011210 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OBUA, CELESTINO · 2018 to 2022
$3.3M
FIC NIH HHS R25 TW011210
6 · The paper itself

Abstract

backgroundDue to improved coverage and scale-up of antiretroviral therapy (ART), patients are increasingly transferring between ART-providing sites. Self-transfers may constitute a high proportion of patients considered lost to follow-up (LTFU), and if overlooked when reporting patients who have dropped out of HIV care, may result in an incorrect estimation of retention. We determined the prevalence of self-transfers, and successful tracing, and identified associated factors among people living with HIV (PLHIV) LTFU from care at public health facilities in Sheema District, Southwestern Uganda.

methodsWe conducted a cross-sectional retrospective medical records review during February and March 2022. We included records of all PLHIV who were LTFU from 2017 to 2021, and who were registered at government-owned ART clinics in Sheema District. LTFU was considered for those who were not taking ART refills for a period of ≥ 3 months. We abstracted demographic and clinical data from medical records at the selected clinics. Participants were traced via phone calls or in-person to ascertain the outcomes of LTFU. We performed multivariate modified Poisson regression to identify factors associated with self-transfer, and successful tracing.

resultsOverall, 740 patients were identified as LTFU from three ART-providing clinics; of these, 560 (76%) were self-transfers. The mean age was 30 (SD ± 10) years, and most (69%, n = 514) were female; the majority (87%, 641/740) were successfully traced. Age (adjusted prevalence ratio [aPR] = 1.13, 95% CI 1.01-1.25, P = 0.026 for those aged 18-30 years compared to > 30 years), female sex (aPR = 1.18, 95% CI 1.11-1.25, P < 0.001), and having WHO clinical stage 1-2 (aPR = 2.34, 95% CI 1.89-3.91, P < 0.001) were significantly associated with self-transfer. Presence of a phone contact in the patient's file (aPR = 1.10, 95% CI 1.01-1.90, P = 0.026) was associated with successful tracing of the patients considered LTFU.

conclusionSelf-transfers accounted for the majority of patients recorded as LTFU, highlighting the need to account for self-transfers among patients considered LTFU, to accurately estimate retention in care. ART-providing facilities should regularly update contact information for PLHIV to enable successful tracing, in the event that the patients are LTFU. This calls for a health-tracking system that easily identifies self-transfers across ART-providing clinics using unique patient identifiers.

Indexed as

HIV InfectionsLost to Follow-UpAdultCross-Sectional StudiesFemaleHumansMaleMedical RecordsRetrospective StudiesUgandaAntiretroviral therapyHIVLoss to follow-upSelf-transferTracingUganda

Identifiers

PMID36127692
PMCPMC9487036

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.