Evidence map›Paper›PMID 36127598›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Detection of 13C-Mannitol and Other Saccharides Using Tandem Mass Spectrometry for Evaluation of Intestinal Permeability or Leaky Gut.

Nicholas E Larkey, Erica M Fatica, Ravinder J Singh

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicholas E LarkeyDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Erica M FaticaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Ravinder J SinghDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Singh.Ravinder@mayo.edu.
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urine tests for intestinal permeability typically detect the secretion of administered saccharides with relatively different absorptions over a designated time period to determine severity of disease. Traditionally, a disaccharide/monosaccharide ratio such as lactulose/mannitol is used. Due to the potential for contamination of mannitol from different foods and commercial products causing an elevated baseline measurement,

Indexed as

MannitolTandem Mass SpectrometryCarbohydratesCarbon IsotopesIntestinal AbsorptionLactuloseMonosaccharidesPermeabilityRhamnoseCarbohydratesCarbon-13Carbon IsotopesLactuloseMannitolMonosaccharidesRhamnose13C MannitolHigh-performance liquid chromatography tandem mass spectrometryIntestinal permeabilityLactuloseLeaky gutMannitolRhamnoseSucralose

Identifiers

PMID36127598
OpenAlexW4296805068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.