ArticleInternational ophthalmology2023
Exploring association between pseudoexfoliation syndrome and ocular aging.
Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Frequency of Exfoliation Syndrome Among Patients Attending an Ophthalmology Outpatient Clinic in the Northeastern Black Sea Coast of Turkey.Healthcare (Basel, Switzerland) · 2026Article
- Exfoliation Syndrome in a Large Vietnamese American Clinic Population: Clinical Characteristics Including Prevalence of Glaucoma and Narrow Angles.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Corneal epithelial thickness in pseudoexfoliation syndrome: an anterior segment optical coherence tomography study.International ophthalmology · 2025Article
- Comparison of anterior segment parameters in primary angle closure suspects and pseudoexfoliation syndrome with occludable angles.International ophthalmology · 2025Article
- Article
- Comparative Functional and Morphological Data of Different IOL Dislocation Treatment Methods.Journal of clinical medicine · 2025Article
- Metabolite Analysis from Protein Deposits.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Lack of evidence for GWAS signals of exfoliation glaucoma working via monogenic loss-of-function mutation in the nearest gene.Human molecular genetics · 2024Article
- Corneal and anterior segment parameters in patients with clinically unilateral pseudoexfoliation syndrome.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Article
- Aqueous humor metabolomic profiling identifies a distinct signature in pseudoexfoliation syndrome.Frontiers in molecular biosciences · 2024Article
- Pseudoexfoliative Syndrome in Cataract Surgery-A Quality Register Study and Health Economic Analysis in the Split-Dalmatia County, Croatia.Journal of clinical medicine · 2023Article
- Article
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Authors and funding
7 authors.
Funding
Abstract
purposeWithin a population-based follow-up study, to examine the 10-year incidence of pseudoexfoliation syndrome (PEX), possible risk factors for PEX and its association with ocular aging of the cornea, lens and retina.
methodsThe baseline examination was conducted in 2006 on a random sample of 1,033 adult participants from Kaunas city (Lithuania) population of whom 631 had ophthalmic examination data at attendance of the 10-year follow-up in 2016. Detailed examination of the anterior and posterior segment of the eye was carried out. After diagnostic mydriasis PEX was diagnosed by the presence of typical grayish-white exfoliation material on the anterior capsule surface of the lens. The participants were divided to PEX and non-PEX groups.
resultsPEX prevalence increased from 9.8 to 34.2% from baseline to 10-year follow-up. Nuclear cataract was common both in the PEX group (66.7%) and in those without PEX (72.2%), but this difference did not reach statistically significantly increased risk of developing cataract in those with PEX (OR 1.2; p = 0.61). Central corneal thickness (CCT) was thinner in the PEX group (529 ± 34 μm) and in the oldest group (525 ± 36 μm) (p < 0.001). Compared to baseline, corneal curvature (CC) became flatter in both groups (7.6 ± 0.27 vs 7.7 ± 0.26 mm; p < 0.001) during the follow-up, but the difference did not reach significance between groups. Corneal astigmatism was most commonly with-the-rule in both groups (37 (50.0%) vs 148 (68.5%); p > 0.05). Age, sex and PEX had no influence on age-related macular degeneration distribution.
conclusionThe prevalence of PEX increased significantly with age in our population, with those with PEX having thinner and flatter corneae, but no difference in cataract and age-related macular degeneration characteristics.
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