Evidence map›Paper›PMID 36127497›Full record

Trial reportScientific reports2022

SGLT2 inhibitors attenuate nephrin loss and enhance TGF-β

Yuan Tian, Xiao-Min Chen, Xian-Ming Liang, Xiao-Bin Wu, Chun-Meng Yao

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuan TianDepartment of Endocrinology and Metabolism, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, 201-209 Hubin South Road, Xiamen, 361004, People's Republic of China.
Xiao-Min ChenDepartment of Endocrinology and Metabolism, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, 201-209 Hubin South Road, Xiamen, 361004, People's Republic of China. chenxiaomin0517@sina.com.
Xian-Ming LiangCenter of Clinical Laboratory, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, 201-209 Hubin South Road, Xiamen, 361004, People's Republic of China.
Xiao-Bin WuDepartment of Endocrinology and Metabolism, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, 201-209 Hubin South Road, Xiamen, 361004, People's Republic of China.
Chun-Meng YaoDepartment of Nephrology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, 201-209 Hubin South Road, Xiamen, 361004, People's Republic of China.
Zhongshan Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effect of SGLT2 inhibitor (SGLT2i) on albuminuria, nephrin (NPH) and transforming-growth-factor-beta

Indexed as

Diabetes Mellitus, Type 2Kidney DiseasesSodium-Glucose Transporter 2 InhibitorsAlbuminuriaC-Reactive ProteinCreatinineFibrosisHumansInflammationInterleukin-6Membrane ProteinsTransforming Growth Factor beta1Tumor Necrosis Factor-alphaC-Reactive ProteinCreatinineInterleukin-6Membrane ProteinsnephrinSodium-Glucose Transporter 2 InhibitorsTransforming Growth Factor beta1Tumor Necrosis Factor-alpha

Identifiers

PMID36127497
PMCPMC9489863
OpenAlexW4296777396

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.