Evidence map›Paper›PMID 36127407›Full record

ReviewPediatric research2023

Artificial and human intelligence for early identification of neonatal sepsis.

Brynne A Sullivan, Sherry L Kausch, Karen D Fairchild

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Pediatrics 4.0: the Transformative Impacts of the Latest Industrial Revolution on Pediatrics.Health care analysis : HCA : journal of health philosophy and policy · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brynne A SullivanDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, USA. bsa4m@virginia.edu.
Sherry L KauschDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Karen D FairchildDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, USA.
University of Virginia · US

Funding

Predictive Informatics Monitoring in the Neonatal Intensive Care UnitR01HD072071 · NICHD · UNIVERSITY OF VIRGINIA · PI KAREN D FAIRCHILD, Brynne Archer Sullivan · 2014 to 2026
$7.6M
Integrated physiomarker, biomarker and clinical predictive analytics for early warning of sepsis and necrotizing enterocolitis in very low birth weight infants.K23HD097254 · NICHD · UNIVERSITY OF VIRGINIA · PI SULLIVAN, BRYNNE ARCHER · 2019 to 2023
$897k
NICHD NIH HHS K23 HD097254NICHD NIH HHS R01 HD072071
6 · The paper itself

Abstract

Artificial intelligence may have a role in the early detection of sepsis in neonates. Machine learning can identify patterns that predict high or increasing risk for clinical deterioration from a sepsis-like illness. In developing this potential addition to NICU care, careful consideration should be given to the data and methods used to develop, validate, and evaluate prediction models. When an AI system alerts clinicians to a change in a patient's condition that warrants a bedside evaluation, human intelligence and experience come into play to determine an appropriate course of action: evaluate and treat or wait and watch closely. With intelligently developed, validated, and implemented AI sepsis systems, both clinicians and patients stand to benefit. IMPACT: This narrative review highlights the application of AI in neonatal sepsis prediction. It describes issues in clinical prediction model development specific to this population. This article reviews the methods, considerations, and literature on neonatal sepsis model development and validation. Challenges of AI technology and potential barriers to using sepsis AI systems in the NICU are discussed.

Indexed as

Neonatal SepsisSepsisArtificial IntelligenceHumansInfant, NewbornIntelligenceModels, StatisticalPrognosis

Identifiers

PMID36127407
PMCPMC11749885
OpenAlexW4296773808

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.