Evidence map›Paper›PMID 36127148›Full record

ArticleTropical medicine & international health : TM & IH2022

Factors associated with antiretroviral therapy use among pregnant women in rural and urban settings in Southern Province, Zambia: 2016-2019.

Juliet A Morales, Mutinta Hamahuwa, Nkumbula Moyo, Jane N Mutanga, Jessica L Schue, Sylvia Maunga, Philip E Thuma, William J Moss, Catherine G Sutcliffe

Open access · greenAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Juliet A MoralesInternational Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID 0000-0001-7231-0188
Mutinta HamahuwaMacha Research Trust, Zambia.
Nkumbula MoyoMacha Research Trust, Zambia.
Jane N MutangaDepartment of Paediatrics and Child Health, Livingstone Central Hospital, Livingstone, Zambia.
Jessica L SchueInternational Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Sylvia MaungaMacha Research Trust, Zambia.
Philip E ThumaMacha Research Trust, Zambia.
William J MossEpidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Catherine G SutcliffeEpidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Johns Hopkins University · USGolden Valley Agricultural Research Trust · ZMLivingstone Hospital · ZA

Funding

Implementation strategies for a new point-of-care test for early infant diagnosisR01AI116324 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MOSS, WILLIAM J · 2015 to 2019
$2.8M
NIAID NIH HHS 5R01AI116324NIAID NIH HHS R01 AI116324
6 · The paper itself

Abstract

objectivesTo assess antiretroviral therapy (ART) coverage among pregnant women living with HIV and compare the characteristics of women who received and did not receive ART during pregnancy in Zambia.

methodsA cross-sectional study was conducted at urban and rural health facilities in Southern Province, Zambia, from 2016 to 2019. Pregnant women living with HIV delivering at study sites were enrolled and administered a questionnaire, and the results of infant diagnostic testing for HIV at birth was documented.

resultsAbout 1184 mother/infant pairs were enrolled. ART coverage was 93.7%. Most women who did not receive ART during pregnancy reported HIV diagnosis at delivery (18.0%) or during pregnancy (57.7%). The primary reported reason for not receiving ART was not wanting to take the drugs. Women who did not receive ART during pregnancy were significantly younger, less likely to have disclosed their HIV-infection status to others, and less likely to have received antenatal care than women who received ART. ART use correlated with higher levels of education in urban but not rural sites. Overall, 1.0% of infants were infected with HIV at birth, including 0.8% of infants born to women who received ART and 4.1% of infants born to women who did not.

conclusionsMost women received ART according to guidelines, resulting in low perinatal transmission rates of HIV to infants. Efforts to increase ART coverage and prevent vertical transmission should focus on identifying incident HIV infections during pregnancy and strengthening counselling for newly diagnosed pregnant women.

Indexed as

Anti-HIV AgentsHIV InfectionsPregnancy Complications, InfectiousCross-Sectional StudiesFemaleHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalParturitionPregnancyPregnant PeopleZambiaAnti-HIV AgentsHIVpaediatricsprevention of mother-to-child HIV transmissionsub-Saharan Africa

Identifiers

PMID36127148
PMCPMC10375440
OpenAlexW4296466695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.