Evidence map›Paper›PMID 36126817›Full record

ArticleThe journal of pain2023

Twenty-year Outcomes of a Pediatric Chronic Abdominal Pain Cohort: Early Adulthood Health Status and Offspring Physical and Behavioral Health.

Amanda L Stone, Isabel Epstein, Stephen Bruehl, Judy Garber, Craig A Smith, Lynn S Walker

Open access · greenAbstract read
In one paragraph

Article in The journal of pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Amanda L StoneDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: amanda.l.stone@vumc.org.
Isabel EpsteinDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Medicine, Health, and Society, Vanderbilt University, Nashville, Tennessee.
Stephen BruehlDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Judy GarberDepartment of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee.
Craig A SmithDepartment of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee.
Lynn S WalkerDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
ILLNESS BEHAVIOR AND SOMATIZATION IN CHILDRENR01HD023264 · NICHD · VANDERBILT UNIVERSITY · PI WALKER, LYNN D. · 1987 to 2011
$3.9M
TIPS: Training in Perioperative ScienceT32GM108554 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire · 2014 to 2026
$3.7M
Biopsychosocial predictors of opioid use for pediatric postsurgical painK23HD104183 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STONE, AMANDA LEIGH · 2021 to 2025
$667k
NCATS NIH HHS UL1 TR000445NICHD NIH HHS K23 HD104183NICHD NIH HHS R01 HD023264NIGMS NIH HHS T32 GM108554
6 · The paper itself

Abstract

Chronic abdominal pain (CAP) represents a common pediatric primary pain disorder that can have long-term effects on physical and mental health into adulthood. Pediatric CAP and Control cohorts recruited in childhood (∼11 years old, T1) and then assessed in emerging adulthood (∼20 years old, T2) were evaluated again for health outcomes in early adulthood (∼30 years old, T3) for the current study. Further, the study evaluated the mental and physical health of offspring of participants who had become parents. Participants who agreed to enroll at T3 (CAP: n = 90, Control: n = 55) completed measures regarding current health, health-related quality of life (HRQoL), and their child's health when applicable. Results indicated close to 20% of the CAP cohort reported recurrent CAP across all 3 timepoints. Participants with current CAP reported poorer HRQoL compared to participants with remitted CAP who reported poorer HRQoL compared to Control participants. The CAP cohort reported higher health-related anxiety compared to the Control cohort regardless of current pain status. CAP compared to Control participants reported greater emotional problems and fewer conduct problems in their children. Longitudinal studies are needed to assess the developmental course of pediatric chronic pain and intergenerational pathways of risk and resilience. Perspective: This article evaluates patterns of chronic abdominal pain from childhood into early adulthood. Patients with pediatric chronic abdominal pain continue to present with health-related anxiety in adulthood and report greater emotional problems in offspring.

Indexed as

Chronic PainQuality of LifeAbdominal PainAdultChildHealth StatusHumansParentsYoung AdultfamilyFunctional abdominal paingastrointestinalirritable bowel syndromelongitudinal

Identifiers

PMID36126817
PMCPMC9789180
OpenAlexW4296181727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.