Evidence map›Paper›PMID 36126402›Full record

ArticleMedical image analysis2022

Cross-modal attention for multi-modal image registration.

Xinrui Song, Hanqing Chao, Xuanang Xu, Hengtao Guo, Sheng Xu, Baris Turkbey, Bradford J Wood, Thomas Sanford, Ge Wang, Pingkun Yan

Abstract read
In one paragraph

Article in Medical image analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
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  7. Opportunities for Interventional Radiology in Transbronchial Interventions.Cardiovascular and interventional radiology · 2026
    Review
  8. Article
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  19. [The dual-stream feature pyramid network based on Mamba and convolution for brain magnetic resonance image registration].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinrui SongDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Hanqing ChaoDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Xuanang XuDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Hengtao GuoDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Sheng XuCenter for Interventional Oncology, Radiology & Imaging Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Baris TurkbeyMolecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Bradford J WoodCenter for Interventional Oncology, Radiology & Imaging Sciences, National Institutes of Health, Bethesda, MD 20892, USA.
Thomas SanfordDepartment of Urology, The State University of New York Upstate Medical University, Syracuse, NY 13210, USA.
Ge WangDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Pingkun YanDepartment of Biomedical Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. Electronic address: yanp2@rpi.edu.

Funding

Real-time prostate lesion tracking during SBRTR01EB027898 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI HANNAN, RAQUIBUL, WANG, JING · 2019 to 2022
$1.4M
Content-based MR-TRUS Fusion without TrackingR21EB028001 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI YAN, PINGKUN · 2019 to 2021
$797k
NIBIB NIH HHS R01 EB027898NIBIB NIH HHS R21 EB028001
6 · The paper itself

Abstract

In the past few years, convolutional neural networks (CNNs) have been proven powerful in extracting image features crucial for medical image registration. However, challenging applications and recent advances in computer vision suggest that CNNs are limited in their ability to understand the spatial correspondence between features, which is at the core of image registration. The issue is further exaggerated when it comes to multi-modal image registration, where the appearances of input images can differ significantly. This paper presents a novel cross-modal attention mechanism for correlating features extracted from the multi-modal input images and mapping such correlation to image registration transformation. To efficiently train the developed network, a contrastive learning-based pre-training method is also proposed to aid the network in extracting high-level features across the input modalities for the following cross-modal attention learning. We validated the proposed method on transrectal ultrasound (TRUS) to magnetic resonance (MR) registration, a clinically important procedure that benefits prostate cancer biopsy. Our experimental results demonstrate that for MR-TRUS registration, a deep neural network embedded with the cross-modal attention block outperforms other advanced CNN-based networks with ten times its size. We also incorporated visualization techniques to improve the interpretability of our network, which helps bring insights into the deep learning based image registration methods. The source code of our work is available at https://github.com/DIAL-RPI/Attention-Reg.

Indexed as

ProstateProstatic NeoplasmsHumansMagnetic Resonance ImagingMaleNeural Networks, ComputerUltrasonographyCross-modal attentionDeep learningMulti-modal registrationProstate caner imaging

Identifiers

PMID36126402
PMCPMC9588729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.