Evidence map›Paper›PMID 36126189›Full record

ArticleAging2022

Protective effect of fluoxetine against oxidative stress induced by renal ischemia-reperfusion injury via the regulation of miR-450b-5p/Nrf2 axis.

Zhiqiang Qin, Hao Wang, Quanliang Dou, Luwei Xu, Zheng Xu, Ruipeng Jia

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhiqiang QinDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Hao WangDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Quanliang DouDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Luwei XuDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Zheng XuDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Ruipeng JiaDepartment of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was performed to assess the protective effect of fluoxetine (FLX) on renal ischemia-reperfusion injury (IRI) via the regulation of miR-450b-5p/Nrf2 axis in male rats.

Indexed as

MicroRNAsReperfusion InjuryAnimalsAntioxidantsApoptosisBiomarkersFluoxetineHypoxiaKidneyMaleNF-E2-Related Factor 2NF-kappa BOxidative StressRatsReactive Oxygen SpeciesAntioxidantsBiomarkersFluoxetineMicroRNAsNF-E2-Related Factor 2NF-kappa BReactive Oxygen SpeciesfluoxetinemiR-450b-5pNrf2oxidative stressrenal ischemia-reperfusion injury

Identifiers

PMID36126189
PMCPMC10781502
OpenAlexW4296789875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.