Observational studyAging clinical and experimental research2022
Z-drugs and falls in nursing home patients: data from the INCUR study.
Observational study in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundZ-drugs are the most prescribed treatment for insomnia, but their negative effect on the body sway can increase the risk of falls.
aimsEvaluating the association between Z-drugs and falls in a resident cohort.
methodsProspective observational study using the data collected in the Incidence of pNeumonia and related ConseqUences in nursing home Residents (INCUR) study.
resultsDuring the one-year follow-up, among the 800 participants (median age 87), 93 individuals fell (64 fracturing and 29 without fracturing). Lower calf circumference (adjusted OR 0.92, 95% CI 0.86-0.97, p = 0.006) and the use of selective serotonin reuptake inhibitors (adjusted OR 1.86, 95% CI 1.1-3.05, p = 0.01) predicted falls, whereas the use of Z-drugs (adjusted OR 2.37, 95% CI 1.13-4.94, p = 0.02) and lower body mass index (adjusted OR 0.9, 95% CI 0.84-0.97, p = 0.005) were associated with falls without fractures.
conclusionsZ-drugs predicted falls without fractures in residents. Alternative strategies to promote sleep in residents should be pursued.
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