Evidence map›Paper›PMID 36125706›Full record

ArticleAlcoholism, clinical and experimental research2022

Temporal trends in alcohol, cannabis, and simultaneous use among 12th-grade U.S. adolescents from 2000 to 2020: Differences by sex, parental education, and race and ethnicity.

Katherine M Keyes, Navdep Kaur, Noah T Kreski, Qixuan Chen, Silvia S Martins, Deborah Hasin, Mark Olfson, Pia M Mauro

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katherine M KeyesDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.ORCID 0000-0002-5624-021X
Navdep KaurDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.ORCID 0000-0003-4400-1665
Noah T KreskiDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Qixuan ChenDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York, USA.
Silvia S MartinsDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.ORCID 0000-0003-3059-9993
Deborah HasinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.ORCID 0000-0002-6533-7021
Mark OlfsonDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Pia M MauroDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.ORCID 0000-0003-2482-8841

Funding

RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
CE19-001, The Columbia Center for Injury Science and Prevention (CCISP)R49CE003094 · CE · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRANAS, CHARLES C. · 2018 to 2023
$4.3M
As adolescent substance use declines, internalizing symptoms increase: identifying high-risk substance using groups and the role of social media, parental supervision, and unsupervised timeR01DA048853 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M. · 2019 to 2023
$2.0M
Multi-level associations between medical marijuana laws and substance use disorder treatmentK01DA045224 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAURO, PIA M. · 2018 to 2022
$878k
ACL HHS R49CE003094NCIPC CDC HHS R49 CE003094NIDA NIH HHS K01 DA045224NIDA NIH HHS R01 DA048853NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

backgroundSimultaneous use of alcohol and cannabis to enhance each other's effect can cause potential harm. Time trends are diverging in adolescent use of alcohol, which is declining, and cannabis, which is increasing among certain subgroups. However, little is known about trends in their simultaneous and non-simultaneous use. Racial and socioeconomic disparities are emerging in cannabis use, which may portend consequences to public health.

methodsThe 2000 to 2020 Monitoring the Future surveys included approximately 38,000 U.S. 12th-grade students with information on simultaneous use and pertinent demographic factors. A 5-level alcohol/cannabis measure included past-year simultaneous use (i.e., alcohol and cannabis use at the same time), non-simultaneous alcohol and cannabis use, alcohol-use-only, cannabis-use-only, and no use. Multinomial logistic regressions estimated associations (adjusted relative risk ratios; aRRR) with time period (2000 to 2004, 2005 to 2009, 2010 to 2014, 2015 to 2020). Models were adjusted and included interactions with sex, race/ethnicity, and parental education.

resultsBetween 2000 and 2020, simultaneous alcohol/cannabis use among 12th graders decreased from 24.4% to 18.7%. From 2015 to 2020 compared to 2000 to 2004, the odds of simultaneous use (adjusted relative risk ratio (aRRR) vs. no use = 0.57, 95% CI [0.50, 0.66]) and alcohol-use-only (aRRR = 0.55, 95% CI [0.49, 0.61]) decreased, while cannabis-use-only odds increased (aRRR = 2.59, 95% CI [1.87, 3.59]). Notably, the prevalence of cannabis-use-only more than doubled from 2011 to 2019. The odds of simultaneous use, alcohol-use-only, and non-simultaneous use of alcohol and cannabis declined more rapidly among males than females, whereas the odds for cannabis-use-only increased faster for females than males. Increases in cannabis-use-only were faster for non-white adolescents.

conclusionSimultaneous use of alcohol and cannabis is declining among U.S. adolescents, but the decline is slower among females than males. Declines in simultaneous use are largely concomitant with historical declines in alcohol use, indicating that a continued focus on reducing alcohol use among adolescents and young adults has extended benefits to other adolescent substance use. However, cannabis use without any reported past-year alcohol use more than doubled in the last decade, a concerning trend.

Indexed as

CannabisAdolescentAlcohol DrinkingEducational StatusEthanolEthnicityFemaleHumansMaleParentsYoung AdultEthanoladolescentalcoholcannabissimultaneous use

Identifiers

PMID36125706
PMCPMC9635013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.