Evidence map›Paper›PMID 36125703›Full record

ArticleClinical journal of gastroenterology2022

A rare case of an enterochromaffin-like neuroendocrine tumor associated with parietal cell dysfunction treated using endoscopic submucosal dissection.

Sho Shiroma, Kayoko Higuchi, Hiroyoshi Ota, Junji Umeno, Mitsuaki Ishioka, Toshiaki Hirasawa, Hiroko Kuba, Takeshi Ono, Ryoji Uchima, Ryoji Nagamura

Abstract readCase Reports
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In one paragraph

Article in Clinical journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sho ShiromaDepartment of Gastroenterology, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan. sho.shiroma2@gmail.com.ORCID http://orcid.org/0000-0001-7597-1790
Kayoko HiguchiDepartment of Surgical Pathology, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan.
Hiroyoshi OtaDepartment of Biomedical Laboratory Sciences, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto-city, Nagano, 390-8621, Japan.
Junji UmenoDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
Mitsuaki IshiokaDepartment of Gastroenterology, Cancer Institute Hospital, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
Toshiaki HirasawaDepartment of Gastroenterology, Cancer Institute Hospital, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
Hiroko KubaDepartment of Gastroenterology, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan.
Takeshi OnoDepartment of Surgery, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan.
Ryoji UchimaDepartment of Surgical Pathology, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan.
Ryoji NagamuraDepartment of Gastroenterology, Okinawa Kyodo Hospital, 4-10-55, Kohagura, Naha-city, Okinawa, 900-8558, Japan.
Naha City Hospital · JPThe Cancer Institute Hospital · JPKyushu University · JPShinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most gastric neuroendocrine tumors (NETs) develop from enterochromaffin-like (ECL) cells. ECL-cell NETs are classically categorized into three types according to their etiology. A 50-year-old woman presented with submucosal tumor-like lesions in the stomach, which were identified via esophagogastroduodenoscopy. Although esophagogastroduodenoscopy and pathological findings of biopsy specimens showed an absence of mucosal atrophy in the body of the stomach, sticky, adherent, dense mucus was observed. All lesions were diagnosed as ECL-cell NETs based on histological examination findings; however, ECL-cell NETs did not apply to any of the classic types I-III categorization based on laboratory, computed tomography, and 24-h intragastric pH monitoring test findings. Endoscopic submucosal dissection of the tumor was performed. Pathological findings of the excised specimen indicated that parietal cell hyperplasia with a protrusion, dilated fundic glands, and endocrine cell hyperplasia in the background mucosa, and parietal cells were not immunostained for the α-subunits of H

Indexed as

Endoscopic Mucosal ResectionNeuroendocrine TumorsStomach NeoplasmsFemaleGastric MucosaHumansHyperplasiaMiddle AgedEndoscopic submucosal dissectionEnterochromaffin-like neuroendocrine tumorParietal cell dysfunction

Identifiers

PMID36125703
OpenAlexW4297855166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.