Carbon Nanostructure-Based DNA Sensor Used for Quickly Detecting Breast Cancer-Associated Genes.

Yingqi Zhang, Jisu Song, Songlin Yang, Jianying Ouyang, Jin Zhang

Open access · goldAbstract read

In one paragraph

Article in Nanoscale research letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.8field-weighted citation impact, top 35% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

N-Doped carbon quantum dot-based ratiometric fluorescent nanosensor platforms for detection of gastric cancer-associated Helicobacter pylori genes.Mikrochimica acta · 2025
Article
Rapid detection of tear lactoferrin for diagnosis of dry eyes by using fluorescence polarization-based aptasensor.Scientific reports · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yingqi ZhangChemical and Biochemical Engineering, University of Western Ontario, London, ON, N6A 5B9, Canada.

Jisu SongSchool of Biomedical Engineering, University of Western Ontario, London, ON, N6A 5B9, Canada.

Songlin YangChemical and Biochemical Engineering, University of Western Ontario, London, ON, N6A 5B9, Canada.

Jianying OuyangNational Research Council Canada, 1200 Montreal Road, Ottawa, ON, K1A 0R6, Canada.

Jin ZhangChemical and Biochemical Engineering, University of Western Ontario, London, ON, N6A 5B9, Canada. jzhang@eng.uwo.ca.

Western University · CANational Research Council Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early diagnosis of breast cancer highly relies on the detection of mutant DNA at low concentrations. Förster resonance energy transfer (FRET) quenching may offer a solution to quickly detect a small amount of single-strand DNA (ssDNA) through the combination of nanomaterials with special luminescence and unique structures of DNA double helix structure. Here, carbon quantum dots (CDs) modified with Capture ssDNA act as the FRET donor which interact with the two-dimensional fluorescence quencher, i.e., graphene oxide nanosheets (GO), to detect breast cancer-associated Target ssDNA at a low concentration. CDs bioconjugated with the designed Capture ssDNA (named CDs-Capture ssDNA) have the maximum fluorescence intensity (I

Indexed as

Carbon quantum dotsDNA sensorFörster resonance energy transfer (FRET) quenchingGraphene oxide

Identifiers

PMID36125561

DOI10.1186/s11671-022-03730-3

PMCPMC9489825

OpenAlexW4296783823

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.